The sound of silence: Activating silent biosynthetic gene clusters in marine microorganisms

QR Code

The sound of silence: Activating silent biosynthetic gene clusters in marine microorganisms

© 2015 by the authors; licensee MDPI, Basel, Switzerland. Unlocking the rich harvest of marine microbial ecosystems has the potential to both safeguard the existence of our species for the future, while also presenting significant lifestyle benefits for commercial gain. However, while significant ad...

Full description

Bibliographic Details
Main Authors:	Reen, F., Romano, S., Dobson, A., O'Gara, Fergal
Format:	Journal Article
Published:	MDPI AG 2015
Online Access:	http://hdl.handle.net/20.500.11937/20558

Similar Items

Identification of secondary metabolite gene clusters in the Pseudovibrio Genus reveals encouraging biosynthetic potential toward the production of novel bioactive compounds
by: Naughton, L., et al.
Published: (2017)

Diversity of Natural Product Biosynthetic Genes in the Microbiome of the Deep Sea Sponges Inflatella pellicula, Poecillastra compressa, and Stelletta normani
by: Borchert, E., et al.
Published: (2016)

Minimum Information about a Biosynthetic Gene cluster
by: Medema, M., et al.
Published: (2015)

Emerging concepts promising new horizons for marine biodiscovery and synthetic biology
by: Reen, F., et al.
Published: (2015)

Genome Sequence of Paracoccus sp. JM45, a Bacterial Strain Isolated from a Marine Sponge with a Dual Quorum Sensing Inhibition Activity.
by: Gutiérrez-Barranquero, J., et al.
Published: (2019)

Harnessing Marine Biocatalytic Reservoirs for Green Chemistry Applications through Metagenomic Technologies
by: Castilla, I., et al.
Published: (2018)

Expansion and conservation of biosynthetic gene clusters in pathogenic Pyrenophora spp.
by: Moolhuijzen, Paula, et al.
Published: (2020)

Marine pseudovibrio sp. as a novel source of antimicrobials
by: Crowley, S., et al.
Published: (2014)

Disruption of N-acyl-homoserine lactone-specific signalling and virulence in clinical pathogens by marine sponge bacteria
by: Gutiérrez-Barranquero, J., et al.
Published: (2018)

Emerging Strategies and Integrated Systems Microbiology Technologies for Biodiscovery of Marine Bioactive Compounds
by: Rocha-Martin, J., et al.
Published: (2014)

Comparative genomic analysis reveals a diverse repertoire of genes involved in prokaryote-eukaryote interactions within the Pseudovibrio Genus
by: Romano, S., et al.
Published: (2016)

Marine Metagenomics: New Tools for the Study and Exploitation of Marine Microbial Metabolism
by: Kennedy, J., et al.
Published: (2010)

Diversity and antibacterial activity of bacteria isolated from the coastal marine sponges Amphilectus fucorum and Eurypon major
by: Margassery, L., et al.
Published: (2012)

Metagenomic strategies for the discovery of novel enzymes with biotechnological application from marine ecosystems
by: Kennedy, J., et al.
Published: (2013)

Tle distribution and diversity in metagenomic datasets reveal niche specialization
by: Egan, F., et al.
Published: (2015)

Maribacter spongiicola sp. nov. and Maribacter vaceletii sp. nov., isolated from marine sponges, and emended description of the genus Maribacter
by: Jackson, S., et al.
Published: (2015)

Evidence of a Putative Deep Sea Specific Microbiome in Marine Sponges
by: Kennedy, J., et al.
Published: (2014)

Endoglucanase activities and growth of marine-derived fungi isolated from the sponge Haliclona simulans
by: Baker, P., et al.
Published: (2010)

Pseudovibrio axinellae sp. nov., isolated from an Irish marine sponge
by: O’Halloran, J., et al.
Published: (2013)

Evolutionary history of the phl gene cluster in the plant-associated bacterium Pseudomonas fluorescens
by: Moynihan, J., et al.
Published: (2009)

Diversity and antimicrobial activities of microbes from two Irish marine sponges, Suberites carnosus and Leucosolenia sp.
by: Flemer, B., et al.
Published: (2012)

Integrated (Meta) genomic and synthetic biology approaches to develop new biocatalysts
by: Parages, M., et al.
Published: (2016)

Identification of the biosynthetic gene clusters for the lipopeptides fusaristatin A and W493 B in Fusarium graminearum and F. pseudograminearum
by: Sørensen, J., et al.
Published: (2014)

Tetracycline resistance-encoding plasmid from Bacillus sp. strain #24, isolated from the marine sponge haliclona simulans
by: Phelan, R., et al.
Published: (2011)

Mining Microbial Signals for Enhanced Biodiscovery of Secondary Metabolites
by: Reen, F., et al.
Published: (2017)

The expanding horizon of alkyl quinolone signalling and communication in polycellular interactomes
by: Reen, F., et al.
Published: (2018)

Heterologous Expression Of Violacein Biosynthetic Gene Cluster From Chromobacterium Violaceum Strain Mth01 In Escherichia Coli
by: Matthew Minggu, Matthlessa
Published: (2017)

Deciphering the role of coumarin as a novel quorum sensing inhibitor suppressing virulence phenotypes in bacterial pathogens
by: Gutiérrez-Barranquero, J., et al.
Published: (2015)

Erratum to: Deciphering the role of coumarin as a novel quorum sensing inhibitor suppressing virulence phenotypes in bacterial pathogens [Appl Microbiol Biotechnol, 10.1007/s00253-015-6436-1]
by: Gutiérrez-Barranquero, J., et al.
Published: (2015)

The Sound of Silence: why music in Supermarkets is just a distraction
by: Hynes, Niki, et al.
Published: (2015)

A non-classical LysR-type transcriptional regulator PA2206 is required for an effective oxidative stress response in Pseudomonas aeruginosa.
by: Reen, F, et al.
Published: (2013)

Is there potential for repurposing statins as novel antimicrobials?
by: Hennessy, E., et al.
Published: (2016)

Characterisation of Non-Autoinducing Tropodithietic Acid (TDA) Production from Marine Sponge Pseudovibrio Species
by: Harrington, C., et al.
Published: (2014)

Functional metagenomic strategies for the discovery of novel enzymes and biosurfactants with biotechnological applications from marine ecosystems
by: Kennedy, J., et al.
Published: (2011)

Evidence of bacteriophage-mediated horizontal transfer of bacterial 16S rRNA genes in the viral metagenome of the marine sponge Hymeniacidon perlevis
by: Harrington, C., et al.
Published: (2012)

Low oxygen induces the type III secretion system in Pseudomonas aeruginosa via modulation of the small RNAs rsmZ and rsmY
by: O'Callaghan, J., et al.
Published: (2011)

A Novel Erythromycin Resistance Plasmid from Bacillus Sp. Strain HS24, Isolated from the Marine Sponge Haliclona Simulans
by: Barbosa, T., et al.
Published: (2014)

Exploitation of glucose catabolic gene fusions to investigate in situ expression during Pseudomonas-plant interactions
by: Rice, O., et al.
Published: (2012)

Gene silencing approaches for the management of dyslipidaemia
by: Norata, Giuseppe, et al.
Published: (2013)

Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome
by: Tan, H., et al.
Published: (2014)