Translation of human tissue factor pathway inhibitor-ß mRNA is controlled by alternative splicing within the 5' untranslated region

QR Code

Translation of human tissue factor pathway inhibitor-ß mRNA is controlled by alternative splicing within the 5' untranslated region

OBJECTIVE - Tissue factor pathway inhibitor (TFPI) blocks the initiation of coagulation by inhibiting TF-activated factor VII, activated factor X, and early prothrombinase. Humans produce two 3' splice variants, TFPIa and TFPIß, which are differentially expressed in endothelial cells and platel...

Full description

Bibliographic Details
Main Authors:	Ellery, Paul, Maroney, S., Martinez, N., Wickens, M., Mast, A.
Format:	Journal Article
Published:	2014
Online Access:	http://hdl.handle.net/20.500.11937/20499

Similar Items

Alternatively spliced isoforms of tissue factor pathway inhibitor
by: Maroney, S., et al.
Published: (2010)

Erratum: Alternatively spliced isoforms of tissue factor pathway inhibitor (Thrombosis research (2010) 125 (s52-s56))
by: Maroney, S., et al.
Published: (2010)

Biology of tissue factor pathway inhibitor
by: Wood, J., et al.
Published: (2014)

Protein S is a cofactor for platelet and endothelial tissue factor pathway inhibitor-a but not for cell surface-associated tissue factor pathway inhibitor
by: Wood, J., et al.
Published: (2014)

Comparison of the inhibitory activities of human tissue factor pathway inhibitor (TFPI)a and TFPIß
by: Maroney, S., et al.
Published: (2013)

Reduced prothrombinase inhibition by tissue factor pathway inhibitor contributes to the factor V Leiden hypercoagulable state
by: Wood, J., et al.
Published: (2017)

Caveolae optimize tissue factor-Factor VIIa inhibitory activity of cell-surface-associated tissue factor pathway inhibitor
by: Maroney, S., et al.
Published: (2012)

Tissue Factor Pathway Inhibitor: Then and Now
by: Ellery, Paul, et al.
Published: (2014)

m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination
by: Haussmann, Irmgard U., et al.
Published: (2016)

Towards understanding pre-mRNA splicing mechanisms and the role of SR proteins
by: Sahebi, Mahbod, et al.
Published: (2016)

Expression and modulation of tissue factor and tissue factor pathway inhibitor in an endothelial cell based model
by: Ellery, Paul E. R.
Published: (2008)

Alternative RNA splicing: contribution to pain and potential therapeutic strategy
by: Donaldson, Lucy F., et al.
Published: (2016)

DEF6 aggregation is linked to active translation and mRNA turnover in T cells
by: Remon, Kerry
Published: (2017)

Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
by: Alshehri, Abdullah Ali, et al.
Published: (2018)

The relationship between miRNA biogenesis and RNA splicing
by: Parsons, Aimee
Published: (2018)

Divergent LIN28-mRNA associations result in translational suppression upon the initiation of differentiation
by: Tan, S., et al.
Published: (2014)

Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors
by: Muthukaruppan, Anita, et al.
Published: (2017)

Alternative splicing and the inhibition of splicing kinases in Alzheimer’s Disease
by: Alalwany, Roaa
Published: (2021)

Functional analysis of mRNA methylation in plants
by: Zhang, Mi
Published: (2018)

Kenapa mRNA jadi pilihan Malaysia?
by: Sinar Harian
Published: (2021)

Will the mRNA vaccines interfere with Oneâs DNA?
by: Mohd Nordin, Musa, et al.
Published: (2021)

Pharmacology of modulators of alternative splicing
by: Bates, David O., et al.
Published: (2017)

Binding interactions of the mRNA regulator CELF1
by: Edwards, John Michael
Published: (2013)

Investigation of components of the mRNA methylation complex in arabidopsis
by: Albalawi, Doha
Published: (2020)

Teknologi mRNA hasilkan vaksin berkesan, selamat
by: Sarchio, Seri Narti Edayu
Published: (2021)

Axonal mRNA localisation and the development of peripheral sensitisation in vitro
by: Arendt-Tranholm, Asta
Published: (2022)

De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation
by: Haas, M., et al.
Published: (2016)

Characterization of Collagen (IV) mRNA in Cell Lines of Breast Cancer
by: Mat Yusof , Afzan, et al.
Published: (2015)

Calpain proteinase mRNA and beta-agonist induced muscle growth
by: Parr, Timothy
Published: (1991)

Molecular biology approaches to quantify subcellular localisation of mRNA therapeutics
by: Smart, Alfredo D.
Published: (2025)

Synthesis and Advanced Characterisation of Nanoparticle Gene Delivery Systems for mRNA therapeutics
by: Khosravi, Rahman
Published: (2025)

Development of ssRNA for therapeutic gene knock-down
by: Powalowska, Paulina Klaudyna
Published: (2017)

Desaturase Delta-6 mRNA Expressions In Highly Unsaturated Fatty Acids Biosynthesis Pathway During Follicle Maturation In Female Zebrafish (Danio rerio)
by: Ishak, Sairatul Dahlianis
Published: (2010)

Acquired factor V deficiency in a patient without evidence of a classical inhibitor
by: Sosa, I., et al.
Published: (2013)

Factors influencing luteal angiogenesis and alternative splicing in the bovine ovary
by: Thompson, Robert F.
Published: (2018)

Transcriptome analysis of mRNA and miRNA in skeletal muscle indicates an important network for differential Residual Feed Intake in pigs
by: Jing, Lu, et al.
Published: (2015)

Part A: RNA Therapeutics. Development and challenges in nanoparticle delivery/ Part B: Synthesis and characterisation of supramolecular polyplexes for mRNA delivery
by: Vasudevan, Akshaya
Published: (2024)

The dynamic role of mRNA m6A methylation in Arabidopsis thaliana and Solanum lycopersicum
by: Chak, Samuel Erwin Seng Chung
Published: (2024)

UPM dan Synthgene meterai kerjasama strategik bangunkan vaksin haiwan berasaskan mRNA
by: Ab Rahim, Ameesya Aghniya
Published: (2025)

mRNA Expression Of Bone Morphogenetic Protein 7 (bmp7) During Folliculogenesis In Zebrafish
by: Lim, Phaik Siew
Published: (2011)

Cannot write session to /tmp/vufind_sessions/sess_s9q17vv6fau8472penk18munpf