Structure-function analysis of the C-3 position in analogues of microbial behavioural modulators HHQ and PQS

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Structure-function analysis of the C-3 position in analogues of microbial behavioural modulators HHQ and PQS

2-Heptyl-3-hydroxy-4-quinolone (PQS) and its precursor 2-heptyl-4-quinolone (HHQ) are key signalling molecules of the important nosocomial pathogen Pseudomonas aeruginosa. We have recently reported an interkingdom dimension to these molecules, influencing key virulence traits in a broad spectrum of...

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Bibliographic Details
Main Authors:	Reen, F., Clarke, S., Legendre, C., McSweeney, C., Eccles, K., Lawrence, S., O'Gara, Fergal, McGlacken, G.
Format:	Journal Article
Published:	Royal Society of Chemistry 2012
Online Access:	http://hdl.handle.net/20.500.11937/19919

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