Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial
Physical activity has been shown to lower levels of inflammatory markers. However, results are inconsistent, indicating different modes of exercise may have different effects on inflammatory cytokines. We aimed to investigate the effects of 12 weeks of moderate-intensity aerobic, resistance, or comb...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Published: |
Springer New York
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/19755 |
| _version_ | 1848750120424701952 |
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| author | Ho, S. Dhaliwal, Satvinder Hills, A. Pal, Sebely |
| author_facet | Ho, S. Dhaliwal, Satvinder Hills, A. Pal, Sebely |
| author_sort | Ho, S. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Physical activity has been shown to lower levels of inflammatory markers. However, results are inconsistent, indicating different modes of exercise may have different effects on inflammatory cytokines. We aimed to investigate the effects of 12 weeks of moderate-intensity aerobic, resistance, or combination exercise on TNF-α and IL-6 compared to no exercise in overweight and obese individuals. TNF-α levels were significantly decreased at week 12 compared to baseline by 20.8 % in the Aerobic group (p = 0.011), 26.9 % in the Resistance group (p = 0.0001), and 32.6 % in the Combination group (p = 0.003). Levels of TNF-α were significantly lower in the Combination compared to the Control group after 12 weeks of exercise training (−22.6 %, p = 0.025) when adjusting for baseline levels. Twelve weeks of moderate-intensity aerobic, resistance, but mainly combination exercise training decreased TNF-α in overweight and obese individuals compared to no exercise. Therefore, combination exercise training may be physiologically relevant in decreasing the risk of developing chronic diseases. |
| first_indexed | 2025-11-14T07:31:47Z |
| format | Journal Article |
| id | curtin-20.500.11937-19755 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:31:47Z |
| publishDate | 2013 |
| publisher | Springer New York |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-197552017-09-13T15:57:05Z Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial Ho, S. Dhaliwal, Satvinder Hills, A. Pal, Sebely overweight obesity tumor necrosis factor-α exercise training interleukin-6 Physical activity has been shown to lower levels of inflammatory markers. However, results are inconsistent, indicating different modes of exercise may have different effects on inflammatory cytokines. We aimed to investigate the effects of 12 weeks of moderate-intensity aerobic, resistance, or combination exercise on TNF-α and IL-6 compared to no exercise in overweight and obese individuals. TNF-α levels were significantly decreased at week 12 compared to baseline by 20.8 % in the Aerobic group (p = 0.011), 26.9 % in the Resistance group (p = 0.0001), and 32.6 % in the Combination group (p = 0.003). Levels of TNF-α were significantly lower in the Combination compared to the Control group after 12 weeks of exercise training (−22.6 %, p = 0.025) when adjusting for baseline levels. Twelve weeks of moderate-intensity aerobic, resistance, but mainly combination exercise training decreased TNF-α in overweight and obese individuals compared to no exercise. Therefore, combination exercise training may be physiologically relevant in decreasing the risk of developing chronic diseases. 2013 Journal Article http://hdl.handle.net/20.500.11937/19755 10.1007/s10753-012-9584-9 Springer New York restricted |
| spellingShingle | overweight obesity tumor necrosis factor-α exercise training interleukin-6 Ho, S. Dhaliwal, Satvinder Hills, A. Pal, Sebely Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial |
| title | Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial |
| title_full | Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial |
| title_fullStr | Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial |
| title_full_unstemmed | Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial |
| title_short | Effects of chronic exercise training on inflammatory markers in Australian overweight and obese individuals in a randomized controlled trial |
| title_sort | effects of chronic exercise training on inflammatory markers in australian overweight and obese individuals in a randomized controlled trial |
| topic | overweight obesity tumor necrosis factor-α exercise training interleukin-6 |
| url | http://hdl.handle.net/20.500.11937/19755 |