Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic ß cells

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic ß cells

Phosphoinositide 3-kinases (PI3Ks) are critical regulators of pancreatic ß cell mass and survival, whereas their involvement in insulin secretion is more controversial. Furthermore, of the different PI3Ks, the class II isoforms were detected in ß cells, although their role is still not well understo...

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Bibliographic Details
Main Authors: Dominguez, V., Raimondi, C., Somanath, S., Bugliani, M., Loder, M., Edling, C., Divecha, N., Silva-Xavier, G., Marselli, L., Persaud, S., Turner, M., Rutter, G., Marchetti, P., Falasca, Marco, Maffucci, T.
Format: Journal Article
Published: 2011
Online Access:http://hdl.handle.net/20.500.11937/19667

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