Chitosan-benzofuran adduct for potential biomedical applications: Improved antibacterial and antifungal properties
Chitosan-benzofuran adduct showed better antifungal and antibacterial properties compared to chitosan or benzofuran alone. The new polymer hydrogel has been characterized using FTIR, SEM, DSC, TGA and XRD. FTIR proved the formation of Schiff’s base reaction at 1632 cm−1, between the chitosan’s amino...
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| Format: | Journal Article |
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Scholars Research Library
2015
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| Online Access: | http://scholarsresearchlibrary.com/dpl-vol7-iss10/DPL-2015-7-10-107-117.pdf http://hdl.handle.net/20.500.11937/19088 |
| _version_ | 1848749933244448768 |
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| author | Elnashar, Magdy Abdel, L. Awad, H. Mouneir, S. |
| author_facet | Elnashar, Magdy Abdel, L. Awad, H. Mouneir, S. |
| author_sort | Elnashar, Magdy |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Chitosan-benzofuran adduct showed better antifungal and antibacterial properties compared to chitosan or benzofuran alone. The new polymer hydrogel has been characterized using FTIR, SEM, DSC, TGA and XRD. FTIR proved the formation of Schiff’s base reaction at 1632 cm−1, between the chitosan’s amino group and the khellinone’s ketonic group. The X-ray diffraction patterns of chitosan-benzofuran showed the formation of a porous xerogel network. The TGA and DSC results were in accordance with the results obtained from the SEM. The TGA and DSC revealed slight loss in the chitosan-benzofuran’ thermal stability compared to chitosan hydrogel and that could be regarded to the increase in porosity as shown in the SEM. The novel chitosan-benzofuran hydrogel has shown an outstanding antifungal and antibacterial effect. Moreover, the cellular cytotoxicity of baby hamster kidney cells culture by adding different concentrations of chitosan-benzofuran hydrogel were greater than those obtained from benzofuran or chitosan alone as they were 4.81±2%, 5.27±2% and 9.43±5%, respectively. |
| first_indexed | 2025-11-14T07:28:48Z |
| format | Journal Article |
| id | curtin-20.500.11937-19088 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:28:48Z |
| publishDate | 2015 |
| publisher | Scholars Research Library |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-190882017-01-30T12:11:51Z Chitosan-benzofuran adduct for potential biomedical applications: Improved antibacterial and antifungal properties Elnashar, Magdy Abdel, L. Awad, H. Mouneir, S. Chitosan-benzofuran adduct showed better antifungal and antibacterial properties compared to chitosan or benzofuran alone. The new polymer hydrogel has been characterized using FTIR, SEM, DSC, TGA and XRD. FTIR proved the formation of Schiff’s base reaction at 1632 cm−1, between the chitosan’s amino group and the khellinone’s ketonic group. The X-ray diffraction patterns of chitosan-benzofuran showed the formation of a porous xerogel network. The TGA and DSC results were in accordance with the results obtained from the SEM. The TGA and DSC revealed slight loss in the chitosan-benzofuran’ thermal stability compared to chitosan hydrogel and that could be regarded to the increase in porosity as shown in the SEM. The novel chitosan-benzofuran hydrogel has shown an outstanding antifungal and antibacterial effect. Moreover, the cellular cytotoxicity of baby hamster kidney cells culture by adding different concentrations of chitosan-benzofuran hydrogel were greater than those obtained from benzofuran or chitosan alone as they were 4.81±2%, 5.27±2% and 9.43±5%, respectively. 2015 Journal Article http://hdl.handle.net/20.500.11937/19088 http://scholarsresearchlibrary.com/dpl-vol7-iss10/DPL-2015-7-10-107-117.pdf Scholars Research Library restricted |
| spellingShingle | Elnashar, Magdy Abdel, L. Awad, H. Mouneir, S. Chitosan-benzofuran adduct for potential biomedical applications: Improved antibacterial and antifungal properties |
| title | Chitosan-benzofuran adduct for potential biomedical applications: Improved antibacterial and antifungal properties |
| title_full | Chitosan-benzofuran adduct for potential biomedical applications: Improved antibacterial and antifungal properties |
| title_fullStr | Chitosan-benzofuran adduct for potential biomedical applications: Improved antibacterial and antifungal properties |
| title_full_unstemmed | Chitosan-benzofuran adduct for potential biomedical applications: Improved antibacterial and antifungal properties |
| title_short | Chitosan-benzofuran adduct for potential biomedical applications: Improved antibacterial and antifungal properties |
| title_sort | chitosan-benzofuran adduct for potential biomedical applications: improved antibacterial and antifungal properties |
| url | http://scholarsresearchlibrary.com/dpl-vol7-iss10/DPL-2015-7-10-107-117.pdf http://hdl.handle.net/20.500.11937/19088 |