Burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a West Australian population based study
Background: While the most obvious impact of burn is on the skin, systemic responses also occur after burn, including intestinal inflammation. The objective of this study was to assess if burns are associated with increased long-term admissions for gastrointestinal diseases. Methods: A population-ba...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
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Pergamon Press
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/18749 |
| _version_ | 1848749833934864384 |
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| author | Stevenson, A. Randall, Sean Boyd, James Wood, F. Fear, M. Duke, J. |
| author_facet | Stevenson, A. Randall, Sean Boyd, James Wood, F. Fear, M. Duke, J. |
| author_sort | Stevenson, A. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: While the most obvious impact of burn is on the skin, systemic responses also occur after burn, including intestinal inflammation. The objective of this study was to assess if burns are associated with increased long-term admissions for gastrointestinal diseases. Methods: A population-based longitudinal study using linked hospital morbidity and death data from Western Australia was undertaken of adults aged at least 15 years when hospitalized for a first burn (n=20,561) in 1980-2012. A frequency matched non-injury comparison cohort was randomly selected from Western Australia's birth registrations and electoral roll (n=80,960). Crude admission rates and summed days in hospital for digestive diseases were calculated. Negative binomial and Cox proportional hazards regression modeling were used to generate incidence rate ratios (IRR) and hazard ratios (HR), respectively. Results: After adjustment for demographic factors and pre-existing health status, the burn cohort had 1.54 times (95% confidence interval (CI): 1.47-1.62) as many admissions and almost three times the number of days in hospital with a digestive system diagnosis (IRR, 95% CI: 2.90, 2.60-3.25) than the uninjured cohort. Significantly elevated adjusted post-burn incident rates were identified, with the risk decreasing with increasing time: in the first month (HR, 95% CI: 3.02, 1.89-4.82), from one month to five years (HR, 95% CI: 1.42, 1.31-1.54), and from five to twenty years after burn (HR, 95% CI: 1.13, 1.06-1.20). Conclusions: Findings of increased hospital admission rates and prolonged length of hospital stay for gastrointestinal diseases in the burn cohort provide evidence to support that burns have effects that persist long after the initial injury. |
| first_indexed | 2025-11-14T07:27:14Z |
| format | Journal Article |
| id | curtin-20.500.11937-18749 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:27:14Z |
| publishDate | 2016 |
| publisher | Pergamon Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-187492017-09-13T15:40:43Z Burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a West Australian population based study Stevenson, A. Randall, Sean Boyd, James Wood, F. Fear, M. Duke, J. Background: While the most obvious impact of burn is on the skin, systemic responses also occur after burn, including intestinal inflammation. The objective of this study was to assess if burns are associated with increased long-term admissions for gastrointestinal diseases. Methods: A population-based longitudinal study using linked hospital morbidity and death data from Western Australia was undertaken of adults aged at least 15 years when hospitalized for a first burn (n=20,561) in 1980-2012. A frequency matched non-injury comparison cohort was randomly selected from Western Australia's birth registrations and electoral roll (n=80,960). Crude admission rates and summed days in hospital for digestive diseases were calculated. Negative binomial and Cox proportional hazards regression modeling were used to generate incidence rate ratios (IRR) and hazard ratios (HR), respectively. Results: After adjustment for demographic factors and pre-existing health status, the burn cohort had 1.54 times (95% confidence interval (CI): 1.47-1.62) as many admissions and almost three times the number of days in hospital with a digestive system diagnosis (IRR, 95% CI: 2.90, 2.60-3.25) than the uninjured cohort. Significantly elevated adjusted post-burn incident rates were identified, with the risk decreasing with increasing time: in the first month (HR, 95% CI: 3.02, 1.89-4.82), from one month to five years (HR, 95% CI: 1.42, 1.31-1.54), and from five to twenty years after burn (HR, 95% CI: 1.13, 1.06-1.20). Conclusions: Findings of increased hospital admission rates and prolonged length of hospital stay for gastrointestinal diseases in the burn cohort provide evidence to support that burns have effects that persist long after the initial injury. 2016 Journal Article http://hdl.handle.net/20.500.11937/18749 10.1016/j.burns.2016.09.009 Pergamon Press restricted |
| spellingShingle | Stevenson, A. Randall, Sean Boyd, James Wood, F. Fear, M. Duke, J. Burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a West Australian population based study |
| title | Burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a West Australian population based study |
| title_full | Burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a West Australian population based study |
| title_fullStr | Burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a West Australian population based study |
| title_full_unstemmed | Burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a West Australian population based study |
| title_short | Burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a West Australian population based study |
| title_sort | burn leads to long-term elevated admissions to hospital for gastrointestinal disease in a west australian population based study |
| url | http://hdl.handle.net/20.500.11937/18749 |