3D QSAR pharmacophore modeling, in silico screening, and density functional theory (DFT) approaches for identification of human chymase inhibitors

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3D QSAR pharmacophore modeling, in silico screening, and density functional theory (DFT) approaches for identification of human chymase inhibitors

Human chymase is a very important target for the treatment of cardiovascular diseases. Using a series of theoretical methods like pharmacophore modeling, database screening, molecular docking and Density Functional Theory (DFT) calculations, an investigation for identification of novel chymase inhib...

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Bibliographic Details
Main Authors:	Arooj, Mahreen, Thangapandian, S., John, S., Hwang, S., Park, J., Lee, K.
Format:	Journal Article
Published:	2011
Online Access:	http://hdl.handle.net/20.500.11937/18615

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