Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months?
An increase in off-season (June to September) Ross River virus (RRV) notifications from the greater Perth metropolitan area was observed from 2006 to 2009. We investigated the increase to determine whether it is likely to have reflected a true increase in off-season cases. A single positive RRV IgM...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
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U.S. National Center for Biotechnology Information
2014
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| Online Access: | http://www.health.gov.au/internet/main/publishing.nsf/Content/cda-cdi3802-pdf-cnt.htm/$FILE/cdi3802c.pdf http://hdl.handle.net/20.500.11937/18485 |
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| author | Selvey, Linda Donelly, J. Lindsay, M. Boddu, S. D'Abrera, V. Smith, D. |
| author_facet | Selvey, Linda Donelly, J. Lindsay, M. Boddu, S. D'Abrera, V. Smith, D. |
| author_sort | Selvey, Linda |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | An increase in off-season (June to September) Ross River virus (RRV) notifications from the greater Perth metropolitan area was observed from 2006 to 2009. We investigated the increase to determine whether it is likely to have reflected a true increase in off-season cases. A single positive RRV IgM test result is sufficient for RRV notification but where follow-up testing was performed, the positive pre- dictive value of an IgM test where IgG was nega- tive was very low in the off-season and also in the season when using the only commercially available test kit. The increase in off-season notifications was not associated with an increase in off-season test- ing. Some Perth laboratories use more stringent notification criteria than the nationally agreed RRV case definition, and the geographical distribution of samples tested varies between laboratories. Our findings make a strong case to change the nationally agreed case definition for RRV to not accept a single IgM positive test result as labora- tory definitive evidence where the IgG is negative. Our study also identified a range of challenges in interpreting changes in seasonal patterns and geo- graphical distribution of RRV. Any such observed changes should be investigated through further data analysis and/or mosquito trapping and test- ing in order to assess validity. |
| first_indexed | 2025-11-14T07:26:00Z |
| format | Journal Article |
| id | curtin-20.500.11937-18485 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:26:00Z |
| publishDate | 2014 |
| publisher | U.S. National Center for Biotechnology Information |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-184852017-10-02T02:26:56Z Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months? Selvey, Linda Donelly, J. Lindsay, M. Boddu, S. D'Abrera, V. Smith, D. notifications surveillance Ross River virus serology An increase in off-season (June to September) Ross River virus (RRV) notifications from the greater Perth metropolitan area was observed from 2006 to 2009. We investigated the increase to determine whether it is likely to have reflected a true increase in off-season cases. A single positive RRV IgM test result is sufficient for RRV notification but where follow-up testing was performed, the positive pre- dictive value of an IgM test where IgG was nega- tive was very low in the off-season and also in the season when using the only commercially available test kit. The increase in off-season notifications was not associated with an increase in off-season test- ing. Some Perth laboratories use more stringent notification criteria than the nationally agreed RRV case definition, and the geographical distribution of samples tested varies between laboratories. Our findings make a strong case to change the nationally agreed case definition for RRV to not accept a single IgM positive test result as labora- tory definitive evidence where the IgG is negative. Our study also identified a range of challenges in interpreting changes in seasonal patterns and geo- graphical distribution of RRV. Any such observed changes should be investigated through further data analysis and/or mosquito trapping and test- ing in order to assess validity. 2014 Journal Article http://hdl.handle.net/20.500.11937/18485 http://www.health.gov.au/internet/main/publishing.nsf/Content/cda-cdi3802-pdf-cnt.htm/$FILE/cdi3802c.pdf U.S. National Center for Biotechnology Information fulltext |
| spellingShingle | notifications surveillance Ross River virus serology Selvey, Linda Donelly, J. Lindsay, M. Boddu, S. D'Abrera, V. Smith, D. Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months? |
| title | Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months? |
| title_full | Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months? |
| title_fullStr | Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months? |
| title_full_unstemmed | Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months? |
| title_short | Ross River Virus Infection Surveillance in the Greater Perth Metropolitan Area – Has There been an Increase in Cases in the Winter Months? |
| title_sort | ross river virus infection surveillance in the greater perth metropolitan area – has there been an increase in cases in the winter months? |
| topic | notifications surveillance Ross River virus serology |
| url | http://www.health.gov.au/internet/main/publishing.nsf/Content/cda-cdi3802-pdf-cnt.htm/$FILE/cdi3802c.pdf http://hdl.handle.net/20.500.11937/18485 |