The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region

Aim: To compare the prevalence of metabolic syndrome (MetS) by combinations of MetS components derived from the National Cholesterol Education Program Adult Treatment Panel III (ATPIII) and International Diabetes Federation (IDF) definitions. Methods: Four studies with ethnically distinct population...

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Main Authors: Lee, Crystal, Huxley, Rachel, Woodward, M., Zimmet, P., Shaw, J., Cho, N., Kim, H., Viali, S., Tominaga, M., Vistisen, D., Borch-Johnsen, K., Colagiuri, S.
Format: Journal Article
Published: Elsevier Ireland Ltd 2008
Online Access:http://hdl.handle.net/20.500.11937/18151
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author Lee, Crystal
Huxley, Rachel
Woodward, M.
Zimmet, P.
Shaw, J.
Cho, N.
Kim, H.
Viali, S.
Tominaga, M.
Vistisen, D.
Borch-Johnsen, K.
Colagiuri, S.
author_facet Lee, Crystal
Huxley, Rachel
Woodward, M.
Zimmet, P.
Shaw, J.
Cho, N.
Kim, H.
Viali, S.
Tominaga, M.
Vistisen, D.
Borch-Johnsen, K.
Colagiuri, S.
author_sort Lee, Crystal
building Curtin Institutional Repository
collection Online Access
description Aim: To compare the prevalence of metabolic syndrome (MetS) by combinations of MetS components derived from the National Cholesterol Education Program Adult Treatment Panel III (ATPIII) and International Diabetes Federation (IDF) definitions. Methods: Four studies with ethnically distinct populations from the Asia-Pacific region were selected from the DETECT-2 study database. The prevalences of combinations of MetS components using the modified ATPIII (modATPIII) and IDF MetS definitions were compared between sexes and across populations. Results: A total of 22,952 participants from Australia, Japan, Korea and Samoa were included. The age-adjusted prevalence of modATPIII MetS varied from 9.4 to 35.8% in men and 10.3 to 57.2% in women; results for IDF were generally higher. Prevalences of the 16 possible MetS component combinations from the modATPIII definition that result in a diagnosis of MetS ranged from 0 to 12.7%. Of those with IDF-defined abdominal obesity, the prevalences of the 11 IDF-defined MetS component combinations ranged from 0.2 to 18.3%. Conclusions: The large variation in the prevalence of possible MetS component combinations to diagnose MetS may explain the different risk of cardiovascular outcomes associated with MetS in different populations, especially since particular combinations of MetS components are associated with different risk of cardiovascular disease. © 2008 Elsevier Ireland Ltd. All rights reserved.
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spelling curtin-20.500.11937-181512018-03-29T09:06:21Z The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region Lee, Crystal Huxley, Rachel Woodward, M. Zimmet, P. Shaw, J. Cho, N. Kim, H. Viali, S. Tominaga, M. Vistisen, D. Borch-Johnsen, K. Colagiuri, S. Aim: To compare the prevalence of metabolic syndrome (MetS) by combinations of MetS components derived from the National Cholesterol Education Program Adult Treatment Panel III (ATPIII) and International Diabetes Federation (IDF) definitions. Methods: Four studies with ethnically distinct populations from the Asia-Pacific region were selected from the DETECT-2 study database. The prevalences of combinations of MetS components using the modified ATPIII (modATPIII) and IDF MetS definitions were compared between sexes and across populations. Results: A total of 22,952 participants from Australia, Japan, Korea and Samoa were included. The age-adjusted prevalence of modATPIII MetS varied from 9.4 to 35.8% in men and 10.3 to 57.2% in women; results for IDF were generally higher. Prevalences of the 16 possible MetS component combinations from the modATPIII definition that result in a diagnosis of MetS ranged from 0 to 12.7%. Of those with IDF-defined abdominal obesity, the prevalences of the 11 IDF-defined MetS component combinations ranged from 0.2 to 18.3%. Conclusions: The large variation in the prevalence of possible MetS component combinations to diagnose MetS may explain the different risk of cardiovascular outcomes associated with MetS in different populations, especially since particular combinations of MetS components are associated with different risk of cardiovascular disease. © 2008 Elsevier Ireland Ltd. All rights reserved. 2008 Journal Article http://hdl.handle.net/20.500.11937/18151 10.1016/j.diabres.2008.05.011 Elsevier Ireland Ltd restricted
spellingShingle Lee, Crystal
Huxley, Rachel
Woodward, M.
Zimmet, P.
Shaw, J.
Cho, N.
Kim, H.
Viali, S.
Tominaga, M.
Vistisen, D.
Borch-Johnsen, K.
Colagiuri, S.
The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region
title The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region
title_full The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region
title_fullStr The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region
title_full_unstemmed The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region
title_short The metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the Asia-Pacific region
title_sort metabolic syndrome identifies a heterogeneous group of metabolic component combinations in the asia-pacific region
url http://hdl.handle.net/20.500.11937/18151