Fine Particulates, Preterm Birth, and Membrane Rupture in Rochester, NY
Background: It remains unclear whether fine particulate (PM2.5) exposure affects risk of preterm birth and prelabor rupture of membranes. Unmeasured, poorly measured, and undiscovered individual-level confounders might have introduced bias into past studies that relied on between-women comparisons....
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Lippincott Williams & Wilkins
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/17951 |
| _version_ | 1848749606403309568 |
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| author | Pereira, Gavin Evans, K. Rich, D. Bracken, M. Bell, M. |
| author_facet | Pereira, Gavin Evans, K. Rich, D. Bracken, M. Bell, M. |
| author_sort | Pereira, Gavin |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: It remains unclear whether fine particulate (PM2.5) exposure affects risk of preterm birth and prelabor rupture of membranes. Unmeasured, poorly measured, and undiscovered individual-level confounders might have introduced bias into past studies that relied on between-women comparisons. Methods: This was a longitudinal study of preterm birth and prelabor rupture of membranes in Rochester, NY, 2004–2012 (N = 3,264 women, N = 7,121 singleton births). We used conditional logistic regression to match pregnancies to the same woman and estimate the odds of each outcome associated with average PM2.5 concentrations during each trimester and whole pregnancy. Results: For preterm birth, adjusted odds ratios (95% confidence interval) for 1 µg/m3 increase in PM2.5 in the first trimester, second trimester, third trimester, and whole pregnancy were 1.11 (1.04, 1.18), 1.09 (1.02, 1.16), 1.06 (1.00, 1.13), and 1.17 (1.07, 1.28), respectively. For prelabor rupture of membranes, corresponding odds ratios were 1.00 (0.97, 1.04), 0.99 (0.96, 1.02), 0.99 (0.96, 1.03), and 0.99 (0.94, 1.04), respectively. Conclusion: Risk of preterm birth was greater for pregnancies with elevated PM2.5 exposure than other pregnancies to the same women at lower exposure. We did not observe an association between PM2.5 concentrations and prelabor rupture of membranes. |
| first_indexed | 2025-11-14T07:23:37Z |
| format | Journal Article |
| id | curtin-20.500.11937-17951 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:23:37Z |
| publishDate | 2016 |
| publisher | Lippincott Williams & Wilkins |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-179512017-09-13T15:44:15Z Fine Particulates, Preterm Birth, and Membrane Rupture in Rochester, NY Pereira, Gavin Evans, K. Rich, D. Bracken, M. Bell, M. Background: It remains unclear whether fine particulate (PM2.5) exposure affects risk of preterm birth and prelabor rupture of membranes. Unmeasured, poorly measured, and undiscovered individual-level confounders might have introduced bias into past studies that relied on between-women comparisons. Methods: This was a longitudinal study of preterm birth and prelabor rupture of membranes in Rochester, NY, 2004–2012 (N = 3,264 women, N = 7,121 singleton births). We used conditional logistic regression to match pregnancies to the same woman and estimate the odds of each outcome associated with average PM2.5 concentrations during each trimester and whole pregnancy. Results: For preterm birth, adjusted odds ratios (95% confidence interval) for 1 µg/m3 increase in PM2.5 in the first trimester, second trimester, third trimester, and whole pregnancy were 1.11 (1.04, 1.18), 1.09 (1.02, 1.16), 1.06 (1.00, 1.13), and 1.17 (1.07, 1.28), respectively. For prelabor rupture of membranes, corresponding odds ratios were 1.00 (0.97, 1.04), 0.99 (0.96, 1.02), 0.99 (0.96, 1.03), and 0.99 (0.94, 1.04), respectively. Conclusion: Risk of preterm birth was greater for pregnancies with elevated PM2.5 exposure than other pregnancies to the same women at lower exposure. We did not observe an association between PM2.5 concentrations and prelabor rupture of membranes. 2016 Journal Article http://hdl.handle.net/20.500.11937/17951 10.1097/EDE.0000000000000366 Lippincott Williams & Wilkins fulltext |
| spellingShingle | Pereira, Gavin Evans, K. Rich, D. Bracken, M. Bell, M. Fine Particulates, Preterm Birth, and Membrane Rupture in Rochester, NY |
| title | Fine Particulates, Preterm Birth, and Membrane Rupture in Rochester, NY |
| title_full | Fine Particulates, Preterm Birth, and Membrane Rupture in Rochester, NY |
| title_fullStr | Fine Particulates, Preterm Birth, and Membrane Rupture in Rochester, NY |
| title_full_unstemmed | Fine Particulates, Preterm Birth, and Membrane Rupture in Rochester, NY |
| title_short | Fine Particulates, Preterm Birth, and Membrane Rupture in Rochester, NY |
| title_sort | fine particulates, preterm birth, and membrane rupture in rochester, ny |
| url | http://hdl.handle.net/20.500.11937/17951 |