The proline-rich tyrosine kinase Pyk2 regulates platelet integrin aIIbß3 outside-in signaling
Background: The proline-rich tyrosine kinase Pyk2 is a focal adhesion kinase expressed in blood platelets, and is activated downstream of G-protein coupled receptors as well as integrin a2ß1. Objective: In this study we have investigated the involvement of Pyk2 in integrin aIIbß3 outside-in signalin...
| Main Authors: | Cipolla, L., Consonni, A., Guidetti, G., Canobbio, I., Okigaki, M., Falasca, Marco, Ciraolo, E., Hirsch, E., Balduini, C., Torti, M. |
|---|---|
| Format: | Journal Article |
| Published: |
2013
|
| Online Access: | http://hdl.handle.net/20.500.11937/17871 |
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