Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics
Essential metals, such as iron and copper, play a critical role in a plethora of cellular processes including cell growth and proliferation. However, concomitantly, excess of these metal ions in the body can have deleterious effects due to their ability to generate cytotoxic reactive oxygen species...
| Main Authors: | Kalinowski, D., Stefani, C., Toyokuni, S., Ganz, T., Anderson, G., Subramaniam, N., Trinder, D., Olynyk, John, Chua, A., Jansson, P., Sahni, S., Lane, D., Merlot, A., Kovacevic, Z., Huang, M., Lee, C., Richardson, D. |
|---|---|
| Format: | Journal Article |
| Published: |
2016
|
| Online Access: | http://hdl.handle.net/20.500.11937/17747 |
Similar Items
Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2a, IRE1a, ATF6 and calmodulin kinase
by: Merlot, A., et al.
Published: (2016)
by: Merlot, A., et al.
Published: (2016)
Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase
by: Merlot, Angelica M., et al.
Published: (2016)
by: Merlot, Angelica M., et al.
Published: (2016)
The regulation of cellular iron metabolism
by: Chua, A., et al.
Published: (2007)
by: Chua, A., et al.
Published: (2007)
Mitochondria: Redox metabolism and dysfunction
by: Kang, J., et al.
Published: (2012)
by: Kang, J., et al.
Published: (2012)
Development Of A System For Measuring Pedal Force In Arm Leg Pedal Exercise
by: Najib, Mohammad Amirul Akmal Mohd
Published: (2021)
by: Najib, Mohammad Amirul Akmal Mohd
Published: (2021)
Changes in gene expression of cholesterol metabolism pathways in mouse models of haemochromatosis
by: Graham, Ross, et al.
Published: (2013)
by: Graham, Ross, et al.
Published: (2013)
Pedal Power Energy Harvesting
by: Sah Azmi, Syeikh Muhammad Haziq
Published: (2018)
by: Sah Azmi, Syeikh Muhammad Haziq
Published: (2018)
Factors contributing to the pedal error or pedal misplacement among malaysian car drivers : A survey
by: Mohamad Zairi, Baharom, et al.
Published: (2023)
by: Mohamad Zairi, Baharom, et al.
Published: (2023)
The medicinal chemistry of novel iron Chelators for the treatment of cancer
by: Kovacevic, Z., et al.
Published: (2011)
by: Kovacevic, Z., et al.
Published: (2011)
Foot-Transmitted Vibration: Automotive Accelerator Pedal-Pad Vibration on Tarmac and Paved Road
by: A. R., Yusoff, et al.
Published: (2019)
by: A. R., Yusoff, et al.
Published: (2019)
Liver and serum iron – discrete regulators of hepatic hepcidin expression
by: Chua, A., et al.
Published: (2011)
by: Chua, A., et al.
Published: (2011)
Pattern of muscle contraction in car pedal control
by: Nor Kamaliana Khamis,, et al.
Published: (2018)
by: Nor Kamaliana Khamis,, et al.
Published: (2018)
Virtual driving simulation for pedal error study
by: Zulkifli, Aidisyahrul Hanif, et al.
Published: (2022)
by: Zulkifli, Aidisyahrul Hanif, et al.
Published: (2022)
Inovasi pedal MTB kurang risiko cedera
by: Tarmiji, Farid Ahmad
Published: (2021)
by: Tarmiji, Farid Ahmad
Published: (2021)
Tekan pedal minyak akan terasa kosong
by: Basaruddin, Aisyah
Published: (2025)
by: Basaruddin, Aisyah
Published: (2025)
Iron overload
by: Siah, C., et al.
Published: (2005)
by: Siah, C., et al.
Published: (2005)
Breast Cancer: A Molecular and Redox Snapshot
by: Raman, D., et al.
Published: (2016)
by: Raman, D., et al.
Published: (2016)
Redox equilibria of iron oxides in aqueous-based magnetite dispersions:Effect of pH and redox potential
by: Pang, S.C., et al.
Published: (2007)
by: Pang, S.C., et al.
Published: (2007)
Pedal Exercise Machine For Physical Rehabilitation Of Stroke Patients
by: Amin, Ahmad Bulya Md
Published: (2019)
by: Amin, Ahmad Bulya Md
Published: (2019)
Liver iron transport
by: Graham, R., et al.
Published: (2007)
by: Graham, R., et al.
Published: (2007)
Non-Hfe iron overload: Is phlebotomy the answer?
by: Hazeldine, S., et al.
Published: (2013)
by: Hazeldine, S., et al.
Published: (2013)
Platelet receptor redox regulation
by: Arthur, J., et al.
Published: (2008)
by: Arthur, J., et al.
Published: (2008)
Bcl-2: A prime regulator of mitochondrial redox metabolism in cancer cells
by: Low, I., et al.
Published: (2011)
by: Low, I., et al.
Published: (2011)
Pedal Error Naturalistic Driving Study Among Malaysian Drivers
by: Mohamad Zairi, Baharom, et al.
Published: (2023)
by: Mohamad Zairi, Baharom, et al.
Published: (2023)
The Role of Hfe in Transferrin-Bound Iron Uptake by Hepatocytes
by: Chua, A., et al.
Published: (2008)
by: Chua, A., et al.
Published: (2008)
Small Signaling Molecules and CO-Releasing Molecules (CORMs) for the Modulation of the Cellular Redox Metabolism
by: Simpson, Peter, et al.
Published: (2016)
by: Simpson, Peter, et al.
Published: (2016)
HCV, Iron, and Oxidative Stress: The New Choreography of Hepcidin
by: Trinder, D., et al.
Published: (2008)
by: Trinder, D., et al.
Published: (2008)
A Review on the Pedal Error Cases Among Car Drivers in Malaysia
by: Nursya Mimie Ayuny, Ismail, et al.
Published: (2024)
by: Nursya Mimie Ayuny, Ismail, et al.
Published: (2024)
Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease
by: Ferrari, P., et al.
Published: (2010)
by: Ferrari, P., et al.
Published: (2010)
Liver oxidative stress, apoptosis, and autophagy are increased in a mouse model of iron overload
by: Chua, A., et al.
Published: (2017)
by: Chua, A., et al.
Published: (2017)
Higher concentrations of serum iron and transferrin saturation but not serum ferritin are associated with cancer outcomes
by: Chua, A., et al.
Published: (2016)
by: Chua, A., et al.
Published: (2016)
Clinical perspectives on hereditary hemochromatosis
by: Ayonrinde, O., et al.
Published: (2008)
by: Ayonrinde, O., et al.
Published: (2008)
High iron and transferrin saturation levels are associated with increased risks of non-skin cancers in women
by: Chua, A., et al.
Published: (2014)
by: Chua, A., et al.
Published: (2014)
Using the morphological chart technique for the design of polymeric-based composite automotive pedals
by: Salit, Mohd Sapuan
Published: (2006)
by: Salit, Mohd Sapuan
Published: (2006)
Pedal basikal MTB dengan sistem kunci magnetik tingkat keselamatan penunggang
by: Universiti Putra Malaysia, Pejabat Strategi Korporat dan Komunikasi
Published: (2021)
by: Universiti Putra Malaysia, Pejabat Strategi Korporat dan Komunikasi
Published: (2021)
Voltammetric characterization of the ferrocene|ferrocenium and cobaltocenium|cobaltocene redox couples in RTILs
by: Rogers, E., et al.
Published: (2008)
by: Rogers, E., et al.
Published: (2008)
From bacteria to cancer exploiting metabolic networks for industrial and therapeutic purposes
by: Tomi Andrino, Claudio
Published: (2023)
by: Tomi Andrino, Claudio
Published: (2023)
Mould flow and component design analysis of polymeric based composite automotive clutch pedals
by: Syed Shaharuddin, Sharifah Imihezri, et al.
Published: (2006)
by: Syed Shaharuddin, Sharifah Imihezri, et al.
Published: (2006)
Practice-led: design factor analysis in developing new Mountain Bike (MTB) pedal
by: Dolah, Mohd Shahrizal, et al.
Published: (2022)
by: Dolah, Mohd Shahrizal, et al.
Published: (2022)
A systematic review and meta-analysis of self-help therapeutic interventions for obsessive-compulsive disorder: Is therapeutic contact key to overall improvement?
by: Pearcy, C., et al.
Published: (2016)
by: Pearcy, C., et al.
Published: (2016)
Similar Items
-
Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2a, IRE1a, ATF6 and calmodulin kinase
by: Merlot, A., et al.
Published: (2016) -
Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase
by: Merlot, Angelica M., et al.
Published: (2016) -
The regulation of cellular iron metabolism
by: Chua, A., et al.
Published: (2007) -
Mitochondria: Redox metabolism and dysfunction
by: Kang, J., et al.
Published: (2012) -
Development Of A System For Measuring Pedal Force In Arm Leg Pedal Exercise
by: Najib, Mohammad Amirul Akmal Mohd
Published: (2021)