A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines
A new, efficient, catalyst-free, one-pot, three-component method for the synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines using 3,5-diamino-1,2,4-triazoles, cyanamide, and triethyl orthoformate is developed. The reaction proceeds smoothly under microwave-assisted heatin...
| Main Authors: | , , |
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| Format: | Journal Article |
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Pergamon
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/17735 |
| _version_ | 1848749542837583872 |
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| author | Kalinina, S. Kalinin, D. Dolzhenko, Anton |
| author_facet | Kalinina, S. Kalinin, D. Dolzhenko, Anton |
| author_sort | Kalinina, S. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | A new, efficient, catalyst-free, one-pot, three-component method for the synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines using 3,5-diamino-1,2,4-triazoles, cyanamide, and triethyl orthoformate is developed. The reaction proceeds smoothly under microwave-assisted heating. Advantages of the method include using easily available reagents, short reaction times, and operational simplicity. |
| first_indexed | 2025-11-14T07:22:36Z |
| format | Journal Article |
| id | curtin-20.500.11937-17735 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:22:36Z |
| publishDate | 2013 |
| publisher | Pergamon |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-177352017-09-13T15:44:34Z A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines Kalinina, S. Kalinin, D. Dolzhenko, Anton Purine isosters Multicomponent reaction Microwave-assisted synthesis Triazines Triazoles A new, efficient, catalyst-free, one-pot, three-component method for the synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines using 3,5-diamino-1,2,4-triazoles, cyanamide, and triethyl orthoformate is developed. The reaction proceeds smoothly under microwave-assisted heating. Advantages of the method include using easily available reagents, short reaction times, and operational simplicity. 2013 Journal Article http://hdl.handle.net/20.500.11937/17735 10.1016/j.tetlet.2013.07.158 Pergamon restricted |
| spellingShingle | Purine isosters Multicomponent reaction Microwave-assisted synthesis Triazines Triazoles Kalinina, S. Kalinin, D. Dolzhenko, Anton A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines |
| title | A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines |
| title_full | A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines |
| title_fullStr | A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines |
| title_full_unstemmed | A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines |
| title_short | A one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines |
| title_sort | one-pot, three-component, microwave-promoted synthesis of 2-amino-substituted 7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazines |
| topic | Purine isosters Multicomponent reaction Microwave-assisted synthesis Triazines Triazoles |
| url | http://hdl.handle.net/20.500.11937/17735 |