Emergence of a new disease as a result of interspecific virulence gene transfer
New diseases of humans, animals and plants emerge regularly. Enhanced virulence on a new host can be facilitated by the acquisition of novel virulence factors. Interspecific gene transfer is known to be a source of such virulence factors in bacterial pathogens (often manifested as pathogenicity isla...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Nature Publishing Group
2006
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/17284 |
| _version_ | 1848749424025534464 |
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| author | Friesen, T. Stukenbrock, E. Liu, Z. Meinhardtb, S. Ling, H. Faris, J. Rasmussen, J. Solomon, P. McDonald, B. Oliver, Richard |
| author_facet | Friesen, T. Stukenbrock, E. Liu, Z. Meinhardtb, S. Ling, H. Faris, J. Rasmussen, J. Solomon, P. McDonald, B. Oliver, Richard |
| author_sort | Friesen, T. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | New diseases of humans, animals and plants emerge regularly. Enhanced virulence on a new host can be facilitated by the acquisition of novel virulence factors. Interspecific gene transfer is known to be a source of such virulence factors in bacterial pathogens (often manifested as pathogenicity islands in the recipient organism(1)) and it has been speculated that interspecific transfer of virulence factors may occur in fungal pathogens(2). Until now, no direct support has been available for this hypothesis. Here we present evidence that a gene encoding a critical virulence factor was transferred from one species of fungal pathogen to another. This gene transfer probably occurred just before 1941, creating a pathogen population with significantly enhanced virulence and leading to the emergence of a new damaging disease of wheat. |
| first_indexed | 2025-11-14T07:20:43Z |
| format | Journal Article |
| id | curtin-20.500.11937-17284 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:20:43Z |
| publishDate | 2006 |
| publisher | Nature Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-172842019-05-22T00:20:38Z Emergence of a new disease as a result of interspecific virulence gene transfer Friesen, T. Stukenbrock, E. Liu, Z. Meinhardtb, S. Ling, H. Faris, J. Rasmussen, J. Solomon, P. McDonald, B. Oliver, Richard SENSITIVITY QUANTITATIVE TRAIT LOCI PYRENOPHORA-TRITICI-REPENTIS FILAMENTOUS FUNGI CAUSAL AGENT TAN SPOT TOXIN EVOLUTION WHEAT STAGONOSPORA-NODORUM New diseases of humans, animals and plants emerge regularly. Enhanced virulence on a new host can be facilitated by the acquisition of novel virulence factors. Interspecific gene transfer is known to be a source of such virulence factors in bacterial pathogens (often manifested as pathogenicity islands in the recipient organism(1)) and it has been speculated that interspecific transfer of virulence factors may occur in fungal pathogens(2). Until now, no direct support has been available for this hypothesis. Here we present evidence that a gene encoding a critical virulence factor was transferred from one species of fungal pathogen to another. This gene transfer probably occurred just before 1941, creating a pathogen population with significantly enhanced virulence and leading to the emergence of a new damaging disease of wheat. 2006 Journal Article http://hdl.handle.net/20.500.11937/17284 10.1038/ng1839 Nature Publishing Group restricted |
| spellingShingle | SENSITIVITY QUANTITATIVE TRAIT LOCI PYRENOPHORA-TRITICI-REPENTIS FILAMENTOUS FUNGI CAUSAL AGENT TAN SPOT TOXIN EVOLUTION WHEAT STAGONOSPORA-NODORUM Friesen, T. Stukenbrock, E. Liu, Z. Meinhardtb, S. Ling, H. Faris, J. Rasmussen, J. Solomon, P. McDonald, B. Oliver, Richard Emergence of a new disease as a result of interspecific virulence gene transfer |
| title | Emergence of a new disease as a result of interspecific virulence gene transfer |
| title_full | Emergence of a new disease as a result of interspecific virulence gene transfer |
| title_fullStr | Emergence of a new disease as a result of interspecific virulence gene transfer |
| title_full_unstemmed | Emergence of a new disease as a result of interspecific virulence gene transfer |
| title_short | Emergence of a new disease as a result of interspecific virulence gene transfer |
| title_sort | emergence of a new disease as a result of interspecific virulence gene transfer |
| topic | SENSITIVITY QUANTITATIVE TRAIT LOCI PYRENOPHORA-TRITICI-REPENTIS FILAMENTOUS FUNGI CAUSAL AGENT TAN SPOT TOXIN EVOLUTION WHEAT STAGONOSPORA-NODORUM |
| url | http://hdl.handle.net/20.500.11937/17284 |