Sedentary behaviors and emerging cardiometabolic biomarkers in adolescents

Objective: To examine the associations of objectively measured sedentary time and television (TV) viewing time with emerging inflammatory and endothelial function markers in adolescents. Study design: This study comprised 183 adolescents (88 girls), aged 13 to 17 years. Sedentary time and moderate-t...

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Main Authors: Martinez-Gomez, D., Eisenmann, J., Healy, Genevieve, Gomez-Martinez, S., Diaz, L., Dunstan, D., Veiga, O., Marcos, A.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/17149
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author Martinez-Gomez, D.
Eisenmann, J.
Healy, Genevieve
Gomez-Martinez, S.
Diaz, L.
Dunstan, D.
Veiga, O.
Marcos, A.
author_facet Martinez-Gomez, D.
Eisenmann, J.
Healy, Genevieve
Gomez-Martinez, S.
Diaz, L.
Dunstan, D.
Veiga, O.
Marcos, A.
author_sort Martinez-Gomez, D.
building Curtin Institutional Repository
collection Online Access
description Objective: To examine the associations of objectively measured sedentary time and television (TV) viewing time with emerging inflammatory and endothelial function markers in adolescents. Study design: This study comprised 183 adolescents (88 girls), aged 13 to 17 years. Sedentary time and moderate-to-vigorous physical activity was objectively measured with accelerometry, whereas TV viewing time was self-reported. White blood cell counts and levels of C-reactive protein, complement factors C3 and C4, interleukin-6, adiponectin, leptin, intercellular adhesion molecule 1, vascular cell adhesion molecule 1, E-selectin, L-selectin, and plasminogen activator inhibitor-1 were measured in fasted blood samples. Results: Sedentary time was not significantly associated with any of the examined cardiometabolic markers after controlling for potential confounders. However, TV viewing time was positively associated with soluble endothelial adhesion molecules intercellular adhesion molecule 1 (standardized ß = 0.19, P =.008), vascular cell adhesion molecule 1 (ß = 0.17, P =.020), L-selectin (ß = 0.18, P =.013), and E-selectin (ß = 0.16, P =.023) concentrations, after controlling for sex, age, pubertal status, moderate-to-vigorous physical activity, body mass index, and total sedentary time. Conclusions: High TV viewing time may play a key role in cardiovascular and metabolic diseases through the cell adhesion molecules in adolescence. Copyright © 2012 Mosby Inc. All rights reserved.
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spelling curtin-20.500.11937-171492017-09-13T15:43:29Z Sedentary behaviors and emerging cardiometabolic biomarkers in adolescents Martinez-Gomez, D. Eisenmann, J. Healy, Genevieve Gomez-Martinez, S. Diaz, L. Dunstan, D. Veiga, O. Marcos, A. Objective: To examine the associations of objectively measured sedentary time and television (TV) viewing time with emerging inflammatory and endothelial function markers in adolescents. Study design: This study comprised 183 adolescents (88 girls), aged 13 to 17 years. Sedentary time and moderate-to-vigorous physical activity was objectively measured with accelerometry, whereas TV viewing time was self-reported. White blood cell counts and levels of C-reactive protein, complement factors C3 and C4, interleukin-6, adiponectin, leptin, intercellular adhesion molecule 1, vascular cell adhesion molecule 1, E-selectin, L-selectin, and plasminogen activator inhibitor-1 were measured in fasted blood samples. Results: Sedentary time was not significantly associated with any of the examined cardiometabolic markers after controlling for potential confounders. However, TV viewing time was positively associated with soluble endothelial adhesion molecules intercellular adhesion molecule 1 (standardized ß = 0.19, P =.008), vascular cell adhesion molecule 1 (ß = 0.17, P =.020), L-selectin (ß = 0.18, P =.013), and E-selectin (ß = 0.16, P =.023) concentrations, after controlling for sex, age, pubertal status, moderate-to-vigorous physical activity, body mass index, and total sedentary time. Conclusions: High TV viewing time may play a key role in cardiovascular and metabolic diseases through the cell adhesion molecules in adolescence. Copyright © 2012 Mosby Inc. All rights reserved. 2012 Journal Article http://hdl.handle.net/20.500.11937/17149 10.1016/j.jpeds.2011.06.037 restricted
spellingShingle Martinez-Gomez, D.
Eisenmann, J.
Healy, Genevieve
Gomez-Martinez, S.
Diaz, L.
Dunstan, D.
Veiga, O.
Marcos, A.
Sedentary behaviors and emerging cardiometabolic biomarkers in adolescents
title Sedentary behaviors and emerging cardiometabolic biomarkers in adolescents
title_full Sedentary behaviors and emerging cardiometabolic biomarkers in adolescents
title_fullStr Sedentary behaviors and emerging cardiometabolic biomarkers in adolescents
title_full_unstemmed Sedentary behaviors and emerging cardiometabolic biomarkers in adolescents
title_short Sedentary behaviors and emerging cardiometabolic biomarkers in adolescents
title_sort sedentary behaviors and emerging cardiometabolic biomarkers in adolescents
url http://hdl.handle.net/20.500.11937/17149