Mushroom Intake and Risk of Epithelial Ovarian Cancer in Southern Chinese Women

OBJECTIVE: This study aimed to investigate the association between mushroom consumption and risk of epithelial ovarian cancer in southern Chinese women.METHODS: A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident pati...

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Main Authors: Lee, Andy, Pasalich, Maria, Su, Dada, Tang, Li, Tran, D., Binns, Colin
Format: Journal Article
Published: Lippincott Williams & Wilkins 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/17134
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author Lee, Andy
Pasalich, Maria
Su, Dada
Tang, Li
Tran, D.
Binns, Colin
author_facet Lee, Andy
Pasalich, Maria
Su, Dada
Tang, Li
Tran, D.
Binns, Colin
author_sort Lee, Andy
building Curtin Institutional Repository
collection Online Access
description OBJECTIVE: This study aimed to investigate the association between mushroom consumption and risk of epithelial ovarian cancer in southern Chinese women.METHODS: A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident patients with epithelial ovarian cancer and 500 controls, with a mean (SD) age of 59 (6) years. Information on habitual mushroom consumption was obtained by face-to-face interview using a validated and reliable food frequency questionnaire. Unconditional logistic regression analyses were performed to assess the association between mushroom intake and the ovarian cancer risk.RESULTS: The patients with ovarian cancer consumed less mushrooms (mean [SD], 28.48 [37.45] g/d) than did controls (mean [SD], 30.75 [41.85] g/d). Apparent reductions in cancer risk were found at high levels of intake, especially for the common white button mushroom with adjusted odds ratios 0.68 (95% confidence interval, 0.52-0.89) for women consuming more than 2 g per day relative to those who consume less than that (P = 0.005). Decreases in risk at high levels of intake were also observed for serous and mucinous subtypes of epithelial ovarian tumors.CONCLUSIONS: Intake of mushrooms, particularly white button mushroom, seemed to be inversely associated with the incidence of epithelial ovarian cancer in southern Chinese women.
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spelling curtin-20.500.11937-171342017-09-13T15:43:30Z Mushroom Intake and Risk of Epithelial Ovarian Cancer in Southern Chinese Women Lee, Andy Pasalich, Maria Su, Dada Tang, Li Tran, D. Binns, Colin Mushroom Epithelial ovarian cancer China OBJECTIVE: This study aimed to investigate the association between mushroom consumption and risk of epithelial ovarian cancer in southern Chinese women.METHODS: A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident patients with epithelial ovarian cancer and 500 controls, with a mean (SD) age of 59 (6) years. Information on habitual mushroom consumption was obtained by face-to-face interview using a validated and reliable food frequency questionnaire. Unconditional logistic regression analyses were performed to assess the association between mushroom intake and the ovarian cancer risk.RESULTS: The patients with ovarian cancer consumed less mushrooms (mean [SD], 28.48 [37.45] g/d) than did controls (mean [SD], 30.75 [41.85] g/d). Apparent reductions in cancer risk were found at high levels of intake, especially for the common white button mushroom with adjusted odds ratios 0.68 (95% confidence interval, 0.52-0.89) for women consuming more than 2 g per day relative to those who consume less than that (P = 0.005). Decreases in risk at high levels of intake were also observed for serous and mucinous subtypes of epithelial ovarian tumors.CONCLUSIONS: Intake of mushrooms, particularly white button mushroom, seemed to be inversely associated with the incidence of epithelial ovarian cancer in southern Chinese women. 2013 Journal Article http://hdl.handle.net/20.500.11937/17134 10.1097/IGC.0b013e3182a41dd8 Lippincott Williams & Wilkins fulltext
spellingShingle Mushroom
Epithelial ovarian cancer
China
Lee, Andy
Pasalich, Maria
Su, Dada
Tang, Li
Tran, D.
Binns, Colin
Mushroom Intake and Risk of Epithelial Ovarian Cancer in Southern Chinese Women
title Mushroom Intake and Risk of Epithelial Ovarian Cancer in Southern Chinese Women
title_full Mushroom Intake and Risk of Epithelial Ovarian Cancer in Southern Chinese Women
title_fullStr Mushroom Intake and Risk of Epithelial Ovarian Cancer in Southern Chinese Women
title_full_unstemmed Mushroom Intake and Risk of Epithelial Ovarian Cancer in Southern Chinese Women
title_short Mushroom Intake and Risk of Epithelial Ovarian Cancer in Southern Chinese Women
title_sort mushroom intake and risk of epithelial ovarian cancer in southern chinese women
topic Mushroom
Epithelial ovarian cancer
China
url http://hdl.handle.net/20.500.11937/17134