Investigation of growth rate dispersion in lactose crystallisation by AFM
α-Lactose monohydrate crystals have been reported to exhibit growth rate dispersion (GRD). Variation in surface dislocations has been suggested as the cause of GRD, but this has not been further investigated to date. In this study, growth rate dispersion and the change in morphology were investigate...
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| Format: | Journal Article |
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Elsevier
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/17081 |
| _version_ | 1848749361334321152 |
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| author | Dincer, Tuna Ogden, Mark Parkinson, Gordon |
| author_facet | Dincer, Tuna Ogden, Mark Parkinson, Gordon |
| author_sort | Dincer, Tuna |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | α-Lactose monohydrate crystals have been reported to exhibit growth rate dispersion (GRD). Variation in surface dislocations has been suggested as the cause of GRD, but this has not been further investigated to date. In this study, growth rate dispersion and the change in morphology were investigated in situ and via bottle roller experiments. The surfaces of the (0 1 0) faces of crystals were examined with Atomic Force Microscopy. Smaller, slow growing crystals tend to have smaller (0 1 0) faces with narrow bases and displayed a single double spiral in the centre of the crystal with 2 nm high steps. Additional double spirals in other crystals resulted in faster growth rates. Large, fast growing crystals were observed to have larger (0 1 0) faces with fast growth in both the a and b directions (giving a broader crystal base) with macro steps parallel to the (c direction). The number and location of spirals or existence of macro steps appears to influence the crystal morphology, growth rates and growth rate dispersion in lactose crystals. |
| first_indexed | 2025-11-14T07:19:43Z |
| format | Journal Article |
| id | curtin-20.500.11937-17081 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:19:43Z |
| publishDate | 2014 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-170812017-09-13T15:44:14Z Investigation of growth rate dispersion in lactose crystallisation by AFM Dincer, Tuna Ogden, Mark Parkinson, Gordon B1. Organic compounds A1. Atomic force microscopy A2. Single crystal growth A1. Optical microscopy A2. Growth from solution α-Lactose monohydrate crystals have been reported to exhibit growth rate dispersion (GRD). Variation in surface dislocations has been suggested as the cause of GRD, but this has not been further investigated to date. In this study, growth rate dispersion and the change in morphology were investigated in situ and via bottle roller experiments. The surfaces of the (0 1 0) faces of crystals were examined with Atomic Force Microscopy. Smaller, slow growing crystals tend to have smaller (0 1 0) faces with narrow bases and displayed a single double spiral in the centre of the crystal with 2 nm high steps. Additional double spirals in other crystals resulted in faster growth rates. Large, fast growing crystals were observed to have larger (0 1 0) faces with fast growth in both the a and b directions (giving a broader crystal base) with macro steps parallel to the (c direction). The number and location of spirals or existence of macro steps appears to influence the crystal morphology, growth rates and growth rate dispersion in lactose crystals. 2014 Journal Article http://hdl.handle.net/20.500.11937/17081 10.1016/j.jcrysgro.2014.06.027 Elsevier fulltext |
| spellingShingle | B1. Organic compounds A1. Atomic force microscopy A2. Single crystal growth A1. Optical microscopy A2. Growth from solution Dincer, Tuna Ogden, Mark Parkinson, Gordon Investigation of growth rate dispersion in lactose crystallisation by AFM |
| title | Investigation of growth rate dispersion in lactose crystallisation by AFM |
| title_full | Investigation of growth rate dispersion in lactose crystallisation by AFM |
| title_fullStr | Investigation of growth rate dispersion in lactose crystallisation by AFM |
| title_full_unstemmed | Investigation of growth rate dispersion in lactose crystallisation by AFM |
| title_short | Investigation of growth rate dispersion in lactose crystallisation by AFM |
| title_sort | investigation of growth rate dispersion in lactose crystallisation by afm |
| topic | B1. Organic compounds A1. Atomic force microscopy A2. Single crystal growth A1. Optical microscopy A2. Growth from solution |
| url | http://hdl.handle.net/20.500.11937/17081 |