ACTIVEDEP: A randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults
Objective: To evaluate the efficacy of a home-based exercise programme added to usual medical care for the treatment of depression. Design: Prospective, two group parallel, randomised controlled study. Setting: Community-based. Patients: 200 adults aged 50 years or older deemed to be currently suffe...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Published: |
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/16931 |
| _version_ | 1848749317618139136 |
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| author | Pfaff, J. Alfonso, Helman Newton, R. Sim, M. Flicker, L. Almeida, O. |
| author_facet | Pfaff, J. Alfonso, Helman Newton, R. Sim, M. Flicker, L. Almeida, O. |
| author_sort | Pfaff, J. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Objective: To evaluate the efficacy of a home-based exercise programme added to usual medical care for the treatment of depression. Design: Prospective, two group parallel, randomised controlled study. Setting: Community-based. Patients: 200 adults aged 50 years or older deemed to be currently suffering from a clinical depressive illness and under the care of a general practitioner. Interventions: Participants were randomly allocated to either usual medical care alone (control) or usual medical care plus physical activity (intervention). The intervention consisted of a 12-week home-based programme to promote physical activity at a level that meets recently published guidelines for exercise in people aged 65 years or over. Main outcome measurements: Severity of depression was measured with the structured interview guide for the Montgomery-Asberg Depression Rating Scale (SIGMA), and depression status was assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Results: Remission of depressive illness was similar in both the usual care (59%) and exercise groups (63%; OR = 1.18, 95% CI 0.61 to 2.30) at the end of the 12-week intervention, and again at the 52-week follow-up (67% vs 68%) (OR=1.07, 95% CI 0.56 to 2.02). There was no change in objective measures of fitness over the 12-week intervention among the exercise group. Conclusions: This home-based physical activity intervention failed to enhance fitness and did not ameliorate depressive symptoms in older adults, possibly due to a lack of ongoing supervision to ensure compliance and optimal engagement. |
| first_indexed | 2025-11-14T07:19:01Z |
| format | Journal Article |
| id | curtin-20.500.11937-16931 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:19:01Z |
| publishDate | 2014 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-169312017-09-13T15:45:17Z ACTIVEDEP: A randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults Pfaff, J. Alfonso, Helman Newton, R. Sim, M. Flicker, L. Almeida, O. Objective: To evaluate the efficacy of a home-based exercise programme added to usual medical care for the treatment of depression. Design: Prospective, two group parallel, randomised controlled study. Setting: Community-based. Patients: 200 adults aged 50 years or older deemed to be currently suffering from a clinical depressive illness and under the care of a general practitioner. Interventions: Participants were randomly allocated to either usual medical care alone (control) or usual medical care plus physical activity (intervention). The intervention consisted of a 12-week home-based programme to promote physical activity at a level that meets recently published guidelines for exercise in people aged 65 years or over. Main outcome measurements: Severity of depression was measured with the structured interview guide for the Montgomery-Asberg Depression Rating Scale (SIGMA), and depression status was assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Results: Remission of depressive illness was similar in both the usual care (59%) and exercise groups (63%; OR = 1.18, 95% CI 0.61 to 2.30) at the end of the 12-week intervention, and again at the 52-week follow-up (67% vs 68%) (OR=1.07, 95% CI 0.56 to 2.02). There was no change in objective measures of fitness over the 12-week intervention among the exercise group. Conclusions: This home-based physical activity intervention failed to enhance fitness and did not ameliorate depressive symptoms in older adults, possibly due to a lack of ongoing supervision to ensure compliance and optimal engagement. 2014 Journal Article http://hdl.handle.net/20.500.11937/16931 10.1136/bjsports-2013-092510 restricted |
| spellingShingle | Pfaff, J. Alfonso, Helman Newton, R. Sim, M. Flicker, L. Almeida, O. ACTIVEDEP: A randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults |
| title | ACTIVEDEP: A randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults |
| title_full | ACTIVEDEP: A randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults |
| title_fullStr | ACTIVEDEP: A randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults |
| title_full_unstemmed | ACTIVEDEP: A randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults |
| title_short | ACTIVEDEP: A randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults |
| title_sort | activedep: a randomised, controlled trial of a home-based exercise intervention to alleviate depression in middle-aged and older adults |
| url | http://hdl.handle.net/20.500.11937/16931 |