Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview
Objective: To describe the approach underpinning a national project to estimate the numbers and proportions of cancers occurring in Australia in 2010 that are attributable to modifiable causal factors. Methods: We estimated the population attributable fraction (PAF) (or prevented fraction) of cancer...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
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Wiley-Blackwell
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/16775 |
| _version_ | 1848749273032687616 |
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| author | Whiteman, D. Webb, P. Green, A. Neale, R. Fritschi, L. Bain, C. Parkin, D. Wilson, L. Olsen, C. Nagle, C. Pandeya, N. Jordan, S. Antonsson, A. Kendall, B. Hughes, M. Ibiebele, T. Miura, K. Peters, S. Carey, Renee |
| author_facet | Whiteman, D. Webb, P. Green, A. Neale, R. Fritschi, L. Bain, C. Parkin, D. Wilson, L. Olsen, C. Nagle, C. Pandeya, N. Jordan, S. Antonsson, A. Kendall, B. Hughes, M. Ibiebele, T. Miura, K. Peters, S. Carey, Renee |
| author_sort | Whiteman, D. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Objective: To describe the approach underpinning a national project to estimate the numbers and proportions of cancers occurring in Australia in 2010 that are attributable to modifiable causal factors. Methods: We estimated the population attributable fraction (PAF) (or prevented fraction) of cancers associated with exposure to causal (or preventive) factors using standard formulae. Where possible, we also estimated the potential impact on cancer incidence resulting from changes in prevalence of exposure. Analyses were restricted to factors declared causal by international agencies: tobacco smoke; alcohol; solar radiation; infectious agents; obesity; insufficient physical activity; insufficient intakes of fruits, vegetables and fibre; red and processed meat; menopausal hormone therapy (MHT); oral contraceptive pill (OCP); and insufficient breast feeding. Separately, we estimated numbers of cancers prevented by: aspirin; sunscreen; MHT; and OCP use. We discuss assumptions pertaining to latent periods between exposure and cancer onset, choices of prevalence data and risk estimates, and approaches to sensitivity analyses. Results: Numbers and population attributable fractions of cancer are presented in accompanying papers. Conclusions: This is the first systematic assessment of population attributable fractions of cancer in Australia. |
| first_indexed | 2025-11-14T07:18:19Z |
| format | Journal Article |
| id | curtin-20.500.11937-16775 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:18:19Z |
| publishDate | 2015 |
| publisher | Wiley-Blackwell |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-167752017-09-13T13:36:44Z Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview Whiteman, D. Webb, P. Green, A. Neale, R. Fritschi, L. Bain, C. Parkin, D. Wilson, L. Olsen, C. Nagle, C. Pandeya, N. Jordan, S. Antonsson, A. Kendall, B. Hughes, M. Ibiebele, T. Miura, K. Peters, S. Carey, Renee Objective: To describe the approach underpinning a national project to estimate the numbers and proportions of cancers occurring in Australia in 2010 that are attributable to modifiable causal factors. Methods: We estimated the population attributable fraction (PAF) (or prevented fraction) of cancers associated with exposure to causal (or preventive) factors using standard formulae. Where possible, we also estimated the potential impact on cancer incidence resulting from changes in prevalence of exposure. Analyses were restricted to factors declared causal by international agencies: tobacco smoke; alcohol; solar radiation; infectious agents; obesity; insufficient physical activity; insufficient intakes of fruits, vegetables and fibre; red and processed meat; menopausal hormone therapy (MHT); oral contraceptive pill (OCP); and insufficient breast feeding. Separately, we estimated numbers of cancers prevented by: aspirin; sunscreen; MHT; and OCP use. We discuss assumptions pertaining to latent periods between exposure and cancer onset, choices of prevalence data and risk estimates, and approaches to sensitivity analyses. Results: Numbers and population attributable fractions of cancer are presented in accompanying papers. Conclusions: This is the first systematic assessment of population attributable fractions of cancer in Australia. 2015 Journal Article http://hdl.handle.net/20.500.11937/16775 10.1111/1753-6405.12468 Wiley-Blackwell unknown |
| spellingShingle | Whiteman, D. Webb, P. Green, A. Neale, R. Fritschi, L. Bain, C. Parkin, D. Wilson, L. Olsen, C. Nagle, C. Pandeya, N. Jordan, S. Antonsson, A. Kendall, B. Hughes, M. Ibiebele, T. Miura, K. Peters, S. Carey, Renee Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview |
| title | Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview |
| title_full | Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview |
| title_fullStr | Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview |
| title_full_unstemmed | Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview |
| title_short | Cancers in Australia in 2010 attributable to modifiable factors: Introduction and overview |
| title_sort | cancers in australia in 2010 attributable to modifiable factors: introduction and overview |
| url | http://hdl.handle.net/20.500.11937/16775 |