Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study
The purpose of the study is to investigate the hemodynamic effect of calcified carotid plaque on blood flow in patients diagnosed with carotid artery disease. Two carotid artery models were generated based on a patient data, with normal and calcified carotid artery appearances. Circular calcified c...
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| Format: | Conference Paper |
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The 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009
2009
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| Online Access: | http://hdl.handle.net/20.500.11937/16419 |
| _version_ | 1848749170958008320 |
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| author | Sun, Zhonghua Ng, Curtise Bibombe, P. Chaichana, T. |
| author2 | The 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009 |
| author_facet | The 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009 Sun, Zhonghua Ng, Curtise Bibombe, P. Chaichana, T. |
| author_sort | Sun, Zhonghua |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The purpose of the study is to investigate the hemodynamic effect of calcified carotid plaque on blood flow in patients diagnosed with carotid artery disease. Two carotid artery models were generated based on a patient data, with normal and calcified carotid artery appearances. Circular calcified carotid plaque was found at the carotid bifurcation based on 3D computed tomography images. A computational fluid dynamics was performed to analyze the changes of blood flow in different situations. Our results showed that apparent turbulence was found in the diastolic phase at the carotid bifurcation in normal carotid artery geometry. In the presence of the calcified plaque, the flow velocity was increased to some extent, indicating the effect of plaque on hemodynamic changes. Wall shear stress was noticed to be maximal at the aortic bifurcation, and this indicates the potential risk of developing stenosis at this area. Our preliminary study demonstrates fluid structure interaction between calcified plaque and artery in terms of flow changes and wall shear stress. |
| first_indexed | 2025-11-14T07:16:41Z |
| format | Conference Paper |
| id | curtin-20.500.11937-16419 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:16:41Z |
| publishDate | 2009 |
| publisher | The 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-164192017-10-02T02:27:38Z Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study Sun, Zhonghua Ng, Curtise Bibombe, P. Chaichana, T. The 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009 Model Calcification Blood flow Computed tomography Carotid artery disease The purpose of the study is to investigate the hemodynamic effect of calcified carotid plaque on blood flow in patients diagnosed with carotid artery disease. Two carotid artery models were generated based on a patient data, with normal and calcified carotid artery appearances. Circular calcified carotid plaque was found at the carotid bifurcation based on 3D computed tomography images. A computational fluid dynamics was performed to analyze the changes of blood flow in different situations. Our results showed that apparent turbulence was found in the diastolic phase at the carotid bifurcation in normal carotid artery geometry. In the presence of the calcified plaque, the flow velocity was increased to some extent, indicating the effect of plaque on hemodynamic changes. Wall shear stress was noticed to be maximal at the aortic bifurcation, and this indicates the potential risk of developing stenosis at this area. Our preliminary study demonstrates fluid structure interaction between calcified plaque and artery in terms of flow changes and wall shear stress. 2009 Conference Paper http://hdl.handle.net/20.500.11937/16419 The 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE) 2009 fulltext |
| spellingShingle | Model Calcification Blood flow Computed tomography Carotid artery disease Sun, Zhonghua Ng, Curtise Bibombe, P. Chaichana, T. Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study |
| title | Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study |
| title_full | Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study |
| title_fullStr | Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study |
| title_full_unstemmed | Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study |
| title_short | Hemodynamic Effect of Calcifed Plaque on Blood Flow in Carotid Artery Disease: A Preliminary Study |
| title_sort | hemodynamic effect of calcifed plaque on blood flow in carotid artery disease: a preliminary study |
| topic | Model Calcification Blood flow Computed tomography Carotid artery disease |
| url | http://hdl.handle.net/20.500.11937/16419 |