Use of quantitative pharmacology tools to improve malaria treatments
The use of pharmacokinetic (PK) and pharmacodynamic (PD) data to inform antimalarial treatment regimens has accelerated in the past few decades, due in no small part to the stimulus provided by progressive development of parasite resistance to most of the currently available drugs. An understanding...
| Main Authors: | Davis, T., Moore, B., Salman, S., Page-Sharp, Madhu, Batty, Kevin, Manning, L. |
|---|---|
| Format: | Journal Article |
| Published: |
2015
|
| Online Access: | http://hdl.handle.net/20.500.11937/16310 |
Similar Items
Piperaquine pharmacodynamics and parasite viability in a murine malaria model
by: Moore, Broni, et al.
Published: (2009)
by: Moore, Broni, et al.
Published: (2009)
Validation and application of a dried blood spot assay for biofilm-active antibiotics commonly used for treatment of prosthetic implant infections
by: Knippenberg, B., et al.
Published: (2016)
by: Knippenberg, B., et al.
Published: (2016)
Pharmacokinetics, Pharmacodynamics and Allometric Scaling of Chloroquine in a Murine Malaria Model
by: Moore, Brioni, et al.
Published: (2011)
by: Moore, Brioni, et al.
Published: (2011)
Penicillin dried blood spot assay for use in patients receiving intramuscular benzathine penicillin G and other penicillin preparations to prevent rheumatic fever
by: Page-Sharp, Madhu, et al.
Published: (2017)
by: Page-Sharp, Madhu, et al.
Published: (2017)
Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria
by: Salman, S., et al.
Published: (2012)
by: Salman, S., et al.
Published: (2012)
Effect of coadministered fat on the tolerability, safety and pharmacokinetic properties of dihydroartemisinin-piperaquine in Papua New Guinean children with uncomplicated malaria
by: Moore, Brioni, et al.
Published: (2014)
by: Moore, Brioni, et al.
Published: (2014)
Treatment regimens for pregnant women with falciparum malaria
by: Moore, Brioni, et al.
Published: (2016)
by: Moore, Brioni, et al.
Published: (2016)
Stability of benzylpenicillin for continuous intravenous infusions: An isotonic formulation for therapeutic use and a low-dose formulation for clinical trial
by: Batty, Kevin, et al.
Published: (2022)
by: Batty, Kevin, et al.
Published: (2022)
Validation and Application of a Dried Blood Spot Ceftriaxone Assay
by: Page-Sharp, M., et al.
Published: (2015)
by: Page-Sharp, M., et al.
Published: (2015)
Ertapenem for osteoarticular infections in obese patients: a pharmacokinetic study of plasma and bone concentrations
by: Chambers, J., et al.
Published: (2018)
by: Chambers, J., et al.
Published: (2018)
Pharmacokinetic properties of single-dose primaquine in Papua New Guinean children: Feasibility of abbreviated high-dose regimens for radical cure of vivax malaria
by: Moore, Brioni, et al.
Published: (2014)
by: Moore, Brioni, et al.
Published: (2014)
Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model
by: Moore, Brioni, et al.
Published: (2008)
by: Moore, Brioni, et al.
Published: (2008)
Simultaneous determination of pentoxifylline, metabolites M1 (lisofylline), M4 and M5, and caffeine in plasma and dried blood spots for pharmacokinetic studies in preterm infants and neonates
by: Page-Sharp, Madhu, et al.
Published: (2017)
by: Page-Sharp, Madhu, et al.
Published: (2017)
Artemisinin-Naphthoquine Combination Therapy for Uncomplicated Pediatric Malaria: a Pharmacokinetic Study
by: Batty, Kevin, et al.
Published: (2012)
by: Batty, Kevin, et al.
Published: (2012)
Plasmodium berghei: Parasite clearance after treatment with dihydroartemisinin in an asplenic murine malaria model
by: Moore, Brioni, et al.
Published: (2008)
by: Moore, Brioni, et al.
Published: (2008)
Naphthoquine: An Emerging Candidate for Artemisinin Combination Therapy
by: Moore, Brioni, et al.
Published: (2016)
by: Moore, Brioni, et al.
Published: (2016)
Bradycardia and hypothermia complicating azithromycin treatment
by: Benn, K., et al.
Published: (2017)
by: Benn, K., et al.
Published: (2017)
Population Pharmacokinetics of Artemether, Lumefantrine, and Their Respective Metabolites in Papua New Guinean Children with Uncomplicated Malaria
by: Salman, S., et al.
Published: (2011)
by: Salman, S., et al.
Published: (2011)
Validation of a dried blood spot ceftriaxone assay in Papua New Guinean children with severe bacterial infections
by: Mukap, M., et al.
Published: (2018)
by: Mukap, M., et al.
Published: (2018)
Development of a pharmacodynamic model of murine malaria and antimalarial treatment with dihydroartemisinin
by: Gibbons, Peter, et al.
Published: (2007)
by: Gibbons, Peter, et al.
Published: (2007)
Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay
by: Page-Sharp, Madhu, et al.
Published: (2012)
by: Page-Sharp, Madhu, et al.
Published: (2012)
Population pharmacokinetic study of ceftriaxone in elderly patients, using cystatin C-based estimates of renal function to account for frailty
by: Tan, S.J., et al.
Published: (2020)
by: Tan, S.J., et al.
Published: (2020)
Pharmacokinetics of piperaquine transfer into the breast milk of Melanesian mothers
by: Moore, B., et al.
Published: (2015)
by: Moore, B., et al.
Published: (2015)
Pharmacodynamics of doxycycline in a murine malaria model
by: Batty, Kevin, et al.
Published: (2007)
by: Batty, Kevin, et al.
Published: (2007)
Pharmacokinetics of dihydroartemisinin in a murine malaria model
by: Batty, Kevin, et al.
Published: (2008)
by: Batty, Kevin, et al.
Published: (2008)
Effects of maturation and size on population pharmacokinetics of pentoxifylline and its metabolites in very preterm infants with suspected late-onset sepsis or necrotizing enterocolitis: a pilot study incorporating clinical outcomes
by: Salman, S., et al.
Published: (2018)
by: Salman, S., et al.
Published: (2018)
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria
by: Karunajeewa, H., et al.
Published: (2008)
by: Karunajeewa, H., et al.
Published: (2008)
Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women
by: Benjamin, J., et al.
Published: (2015)
by: Benjamin, J., et al.
Published: (2015)
Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: A randomized, crossover, population pharmacokinetic study in healthy adult volunteers
by: Kado, J.H., et al.
Published: (2020)
by: Kado, J.H., et al.
Published: (2020)
The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children
by: Sugiarto, S.R., et al.
Published: (2022)
by: Sugiarto, S.R., et al.
Published: (2022)
Retinol supplementation in murine Plasmodium berghei malaria: Effects on tissue levels, parasitaemia and lipid peroxidation
by: Hamzah, J., et al.
Published: (2007)
by: Hamzah, J., et al.
Published: (2007)
Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model
by: Patel, K., et al.
Published: (2014)
by: Patel, K., et al.
Published: (2014)
Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria
by: Patel, K., et al.
Published: (2013)
by: Patel, K., et al.
Published: (2013)
Cost-effectiveness of artemisinin-naphthoquine versus artemether-lumefantrine for the treatment of uncomplicated malaria in Papua New Guinean children
by: Moore, Brioni, et al.
Published: (2017)
by: Moore, Brioni, et al.
Published: (2017)
PHARMACOKINETICS OF TRANSFER OF PIPERAQUINE INTO THE BREAST MILK OF PAPUA NEW GUINEAN MOTHERS
by: Moore, B., et al.
Published: (2015)
by: Moore, B., et al.
Published: (2015)
Pharmacotherapy for the prevention of malaria in pregnant women: currently available drugs and challenges
by: Moore, Brioni, et al.
Published: (2018)
by: Moore, Brioni, et al.
Published: (2018)
Investigation of reproductive toxicology in piperaquine in mice
by: Batty, Kevin, et al.
Published: (2010)
by: Batty, Kevin, et al.
Published: (2010)
Artemisinin therapy for malaria in hemoglobinopathies: A systematic review
by: Sugiarto, S., et al.
Published: (2018)
by: Sugiarto, S., et al.
Published: (2018)
Gametocyte clearance kinetics determined by quantitative magnetic fractionation in Melanesian children with uncomplicated malaria treated with artemisinin combination therapy
by: Karl, S., et al.
Published: (2015)
by: Karl, S., et al.
Published: (2015)
Continuous Infusions of Meropenem in Ambulatory Care: Clinical Efficacy, Safety and Stability
by: Manning, L., et al.
Published: (2014)
by: Manning, L., et al.
Published: (2014)
Similar Items
-
Piperaquine pharmacodynamics and parasite viability in a murine malaria model
by: Moore, Broni, et al.
Published: (2009) -
Validation and application of a dried blood spot assay for biofilm-active antibiotics commonly used for treatment of prosthetic implant infections
by: Knippenberg, B., et al.
Published: (2016) -
Pharmacokinetics, Pharmacodynamics and Allometric Scaling of Chloroquine in a Murine Malaria Model
by: Moore, Brioni, et al.
Published: (2011) -
Penicillin dried blood spot assay for use in patients receiving intramuscular benzathine penicillin G and other penicillin preparations to prevent rheumatic fever
by: Page-Sharp, Madhu, et al.
Published: (2017) -
Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria
by: Salman, S., et al.
Published: (2012)