Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults
Background: To investigate the association between caffeine intake and the risk of developing chronic obstructive pulmonary disease (COPD) among Japanese older adults, a case–control study was conducted in central Japan. Methods: A total of 277 patients with COPD aged 50 to 75 years were referred by...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Mary Ann Liebert, Inc. Publishers
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/15932 |
| _version_ | 1848749030019956736 |
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| author | Hirayama, Fumi Lee, Andy Yasukawa, K. Ishihara, Y. Shinjo, M. |
| author_facet | Hirayama, Fumi Lee, Andy Yasukawa, K. Ishihara, Y. Shinjo, M. |
| author_sort | Hirayama, Fumi |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: To investigate the association between caffeine intake and the risk of developing chronic obstructive pulmonary disease (COPD) among Japanese older adults, a case–control study was conducted in central Japan. Methods: A total of 277 patients with COPD aged 50 to 75 years were referred by respiratory physicians, while 340 controls were recruited from the community. All participants had their disease status confirmed by spirometry. Information on habitual caffeine intake, demographic, and lifestyle characteristics was obtained by face-to-face interview using a validated questionnaire. Results: The COPD patients drank more coffee and had a higher mean caffeine intake (311.3, SD 176.2mg/day) than the control group (278.4, SD 188.1 mg/day), p = 0.03. Relative to nondrinkers, the risk of COPD apparently increased for those drinking at least two cups of coffee daily (adjusted odds ratio 1.58, 95% confidence interval [CI] 0.93 to 2.71). Similarly, total caffeine intake was associated with the prevalence of COPD—the adjusted odds ratio being 1.30 (95% CI 1.09 to 2.12) for consuming over 312mg/day when compared to a low intake of less than 184mg/day. Conclusions: The epidemiological evidence suggested a positive association between caffeine intake and the development of COPD in Japanese adults. Further study of the effect of caffeine on lung function and the risk of COPD should be undertaken. |
| first_indexed | 2025-11-14T07:14:27Z |
| format | Journal Article |
| id | curtin-20.500.11937-15932 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:14:27Z |
| publishDate | 2012 |
| publisher | Mary Ann Liebert, Inc. Publishers |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-159322017-09-13T16:00:27Z Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults Hirayama, Fumi Lee, Andy Yasukawa, K. Ishihara, Y. Shinjo, M. Background: To investigate the association between caffeine intake and the risk of developing chronic obstructive pulmonary disease (COPD) among Japanese older adults, a case–control study was conducted in central Japan. Methods: A total of 277 patients with COPD aged 50 to 75 years were referred by respiratory physicians, while 340 controls were recruited from the community. All participants had their disease status confirmed by spirometry. Information on habitual caffeine intake, demographic, and lifestyle characteristics was obtained by face-to-face interview using a validated questionnaire. Results: The COPD patients drank more coffee and had a higher mean caffeine intake (311.3, SD 176.2mg/day) than the control group (278.4, SD 188.1 mg/day), p = 0.03. Relative to nondrinkers, the risk of COPD apparently increased for those drinking at least two cups of coffee daily (adjusted odds ratio 1.58, 95% confidence interval [CI] 0.93 to 2.71). Similarly, total caffeine intake was associated with the prevalence of COPD—the adjusted odds ratio being 1.30 (95% CI 1.09 to 2.12) for consuming over 312mg/day when compared to a low intake of less than 184mg/day. Conclusions: The epidemiological evidence suggested a positive association between caffeine intake and the development of COPD in Japanese adults. Further study of the effect of caffeine on lung function and the risk of COPD should be undertaken. 2012 Journal Article http://hdl.handle.net/20.500.11937/15932 10.1089/caf.2012.0029 Mary Ann Liebert, Inc. Publishers fulltext |
| spellingShingle | Hirayama, Fumi Lee, Andy Yasukawa, K. Ishihara, Y. Shinjo, M. Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults |
| title | Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults |
| title_full | Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults |
| title_fullStr | Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults |
| title_full_unstemmed | Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults |
| title_short | Caffeine intake and the risk of chronic obstructive pulmonary disease in Japanese adults |
| title_sort | caffeine intake and the risk of chronic obstructive pulmonary disease in japanese adults |
| url | http://hdl.handle.net/20.500.11937/15932 |