Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review

Objectives: To determine the effects of exercise training on exercise capacity, health-related quality of life (HRQoL), lung function (forced expiratory volume in one second (FEV1)) and quadriceps force in people who have had a recent lung resection for non-small cell lung cancer (NSCLC).Data source...

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Main Authors: Cavalheri, Vinicius, Tahirah, F., Nonoyama, M., Jenkins, Susan, Hill, Kylie
Format: Journal Article
Published: W B Saunders co Ltd 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/15758
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author Cavalheri, Vinicius
Tahirah, F.
Nonoyama, M.
Jenkins, Susan
Hill, Kylie
author_facet Cavalheri, Vinicius
Tahirah, F.
Nonoyama, M.
Jenkins, Susan
Hill, Kylie
author_sort Cavalheri, Vinicius
building Curtin Institutional Repository
collection Online Access
description Objectives: To determine the effects of exercise training on exercise capacity, health-related quality of life (HRQoL), lung function (forced expiratory volume in one second (FEV1)) and quadriceps force in people who have had a recent lung resection for non-small cell lung cancer (NSCLC).Data sources: We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, SciELO and PEDro up to February 2013. Review methods: We included randomised controlled trials (RCTs) in which study participants with NSCLC, who had recently undergone lung resection, were allocated to receive either exercise training or no exercise training. Two review authors screened and identified the studies for inclusion. Results: We identified three RCTs involving 178 participants. On completion of the intervention period, exercise capacity, as measured by the six-minute walk distance, was statistically greater in the intervention group compared to the control group (mean difference (MD) 50.4 m; 95% confidence interval (CI) 15.4–85.2 m). No between-group differences were observed in HRQoL (standardised mean difference (SMD) 0.17; 95% CI -0.16–0.49) or FEV1 (MD -0.13 L; 95% CI -0.36–0.11 L). Differences in quadriceps force were not demonstrated on completion of the intervention period. Conclusions: Evidence from our review suggests that exercise training may potentially increase the exercise capacity of people following lung resection for NSCLC. The findings of this review should be interpreted with caution due to disparities between the studies, methodological limitations, some significant risks of bias and small sample sizes.
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spelling curtin-20.500.11937-157582017-09-13T14:07:14Z Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review Cavalheri, Vinicius Tahirah, F. Nonoyama, M. Jenkins, Susan Hill, Kylie Lung resection Exercise training Exercise capacity Non-small cell lung Carcinoma Objectives: To determine the effects of exercise training on exercise capacity, health-related quality of life (HRQoL), lung function (forced expiratory volume in one second (FEV1)) and quadriceps force in people who have had a recent lung resection for non-small cell lung cancer (NSCLC).Data sources: We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, SciELO and PEDro up to February 2013. Review methods: We included randomised controlled trials (RCTs) in which study participants with NSCLC, who had recently undergone lung resection, were allocated to receive either exercise training or no exercise training. Two review authors screened and identified the studies for inclusion. Results: We identified three RCTs involving 178 participants. On completion of the intervention period, exercise capacity, as measured by the six-minute walk distance, was statistically greater in the intervention group compared to the control group (mean difference (MD) 50.4 m; 95% confidence interval (CI) 15.4–85.2 m). No between-group differences were observed in HRQoL (standardised mean difference (SMD) 0.17; 95% CI -0.16–0.49) or FEV1 (MD -0.13 L; 95% CI -0.36–0.11 L). Differences in quadriceps force were not demonstrated on completion of the intervention period. Conclusions: Evidence from our review suggests that exercise training may potentially increase the exercise capacity of people following lung resection for NSCLC. The findings of this review should be interpreted with caution due to disparities between the studies, methodological limitations, some significant risks of bias and small sample sizes. 2014 Journal Article http://hdl.handle.net/20.500.11937/15758 10.1016/j.ctrv.2013.11.001 W B Saunders co Ltd restricted
spellingShingle Lung resection
Exercise training
Exercise capacity
Non-small cell lung
Carcinoma
Cavalheri, Vinicius
Tahirah, F.
Nonoyama, M.
Jenkins, Susan
Hill, Kylie
Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review
title Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review
title_full Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review
title_fullStr Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review
title_full_unstemmed Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review
title_short Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review
title_sort exercise training for people following lung resection for non-small cell lung cancer - a cochrane systematic review
topic Lung resection
Exercise training
Exercise capacity
Non-small cell lung
Carcinoma
url http://hdl.handle.net/20.500.11937/15758