Functional α,ω-dienes via thiol-Michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (ADMET) polymerization and radical thiol–ene modification

The synthesis of the novel α,ω-diene 2-(undec-10-en-1-yl)tridec-12-en-1-yl acrylate is described. Thiol-Michael coupling of this substrate followed by chemoselective oxidation of the thioether moiety with triazotriphosphorine tetrachloride (TAPC) furnished a suite of functional and symmetrical ADMET...

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Main Authors: van Hensbergen, J., Gaines, T., Wagener, K., Burford, R., Lowe, Andrew
Format: Journal Article
Published: R S C Publications 2014
Online Access:http://hdl.handle.net/20.500.11937/15406
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author van Hensbergen, J.
Gaines, T.
Wagener, K.
Burford, R.
Lowe, Andrew
author_facet van Hensbergen, J.
Gaines, T.
Wagener, K.
Burford, R.
Lowe, Andrew
author_sort van Hensbergen, J.
building Curtin Institutional Repository
collection Online Access
description The synthesis of the novel α,ω-diene 2-(undec-10-en-1-yl)tridec-12-en-1-yl acrylate is described. Thiol-Michael coupling of this substrate followed by chemoselective oxidation of the thioether moiety with triazotriphosphorine tetrachloride (TAPC) furnished a suite of functional and symmetrical ADMET-active monomers in a quick and convenient manner. Polymerization of these adducts with Grubbs 1st generation catalyst (RuCl2(PCy3)2CHPh) was demonstrated to high conversion, and quantitative radical initiated thiol–ene modification of the backbone C[double bond, length as m-dash]C bonds was performed to impart additional functionality to each ADMET polymer. These reactions highlight the compatibility of thiol-based click chemistries for the preparation and post-modification of functional ADMET materials.
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institution Curtin University Malaysia
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publishDate 2014
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spelling curtin-20.500.11937-154062017-09-13T13:41:02Z Functional α,ω-dienes via thiol-Michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (ADMET) polymerization and radical thiol–ene modification van Hensbergen, J. Gaines, T. Wagener, K. Burford, R. Lowe, Andrew The synthesis of the novel α,ω-diene 2-(undec-10-en-1-yl)tridec-12-en-1-yl acrylate is described. Thiol-Michael coupling of this substrate followed by chemoselective oxidation of the thioether moiety with triazotriphosphorine tetrachloride (TAPC) furnished a suite of functional and symmetrical ADMET-active monomers in a quick and convenient manner. Polymerization of these adducts with Grubbs 1st generation catalyst (RuCl2(PCy3)2CHPh) was demonstrated to high conversion, and quantitative radical initiated thiol–ene modification of the backbone C[double bond, length as m-dash]C bonds was performed to impart additional functionality to each ADMET polymer. These reactions highlight the compatibility of thiol-based click chemistries for the preparation and post-modification of functional ADMET materials. 2014 Journal Article http://hdl.handle.net/20.500.11937/15406 10.1039/c4py00783b R S C Publications restricted
spellingShingle van Hensbergen, J.
Gaines, T.
Wagener, K.
Burford, R.
Lowe, Andrew
Functional α,ω-dienes via thiol-Michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (ADMET) polymerization and radical thiol–ene modification
title Functional α,ω-dienes via thiol-Michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (ADMET) polymerization and radical thiol–ene modification
title_full Functional α,ω-dienes via thiol-Michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (ADMET) polymerization and radical thiol–ene modification
title_fullStr Functional α,ω-dienes via thiol-Michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (ADMET) polymerization and radical thiol–ene modification
title_full_unstemmed Functional α,ω-dienes via thiol-Michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (ADMET) polymerization and radical thiol–ene modification
title_short Functional α,ω-dienes via thiol-Michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (ADMET) polymerization and radical thiol–ene modification
title_sort functional α,ω-dienes via thiol-michael chemistry: synthesis, oxidative protection, acyclic diene metathesis (admet) polymerization and radical thiol–ene modification
url http://hdl.handle.net/20.500.11937/15406