Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12

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Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12

Structure-guided approaches to HIV-1 vaccine design depend on knowledge of the presentation of neutralizing epitopes on gp120, such as the epitope for the broadly neutralizing mAb b12. Here, we characterized predicted three-dimensional structures of functionally diverse gp120 proteins in their b12-b...

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Bibliographic Details
Main Authors:	Sterjovski, J., Churchill, M., Ellett, A., Wesselingh, S., Ramsland, Paul, Gorry, P.
Format:	Journal Article
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/14643

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