The transcriptional landscape of age in human peripheral blood

The transcriptional landscape of age in human peripheral blood

Disease incidences increase with age, but the molecular characteristics of ageing that lead to increased disease susceptibility remain inadequately understood. Here we perform a whole-blood gene expression meta-analysis in 14,983 individuals of European ancestry (including replication) and identify...

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Main Authors: Peters, M., Joehanes, R., Pilling, L., Schurmann, C., Conneely, K., Powell, J., Reinmaa, E., Sutphin, G., Zhernakova, A., Schramm, K., Wilson, Y., Kobes, S., Tukiainen, T., Ramos, Y., Göring, H., Fornage, M., Liu, Y., Gharib, S., Stranger, B., De Jager, P., Aviv, A., Levy, D., Murabito, J., Munson, P., Huan, T., Hofman, A., Uitterlinden, A., Rivadeneira, F., Van Rooij, J., Stolk, L., Broer, L., Verbiest, M., Jhamai, M., Arp, P., Metspalu, A., Tserel, L., Milani, L., Samani, N., Peterson, P., Kasela, S., Codd, V., Peters, A., Ward-Caviness, C., Herder, C., Waldenberger, M., Roden, M., Singmann, P., Zeilinger, S., Illig, T., Homuth, G., Grabe, H., Völzke, H., Steil, L., Kocher, T., Murray, A., Melzer, D., Yaghootkar, H., Bandinelli, S., Moses, Eric, Kent, J., Curran, J., Johnson, M., Williams-Blangero, S., Westra, H., McRae, A., Smith, J., Kardia, S., Hovatta, I., Perola, M., Ripatti, S., Salomaa, V., Henders, A.
Format: Journal Article
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/14537

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