The role of b-type natriuretic peptide in heart failure management
Summary. Heart failure is a complex clinical syndrome that manifests itself with signs and symptoms which are neither sensitive nor specific for the diagnosis of heart failure. Natriuretic peptides and in particular b-type natriuretic peptide (and nt-proBNP) are widely used in clinical practice aro...
| Main Authors: | , , |
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| Format: | Journal Article |
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Elsevier Inc
2009
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| Online Access: | http://hdl.handle.net/20.500.11937/14305 |
| _version_ | 1848748588179390464 |
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| author | Newton, Phillip Betihavas, Vasiliki Macdonald, P. |
| author_facet | Newton, Phillip Betihavas, Vasiliki Macdonald, P. |
| author_sort | Newton, Phillip |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Summary. Heart failure is a complex clinical syndrome that manifests itself with signs and symptoms which are neither sensitive nor specific for the diagnosis of heart failure. Natriuretic peptides and in particular b-type natriuretic peptide (and nt-proBNP) are widely used in clinical practice around the world as a maker of heart failure. BNP is primarly released from the left ventricle in response to pressure and volume overload. The strongest evidence for the use of BNP is to rule in or rule out heart failure as cause of breathlessness in people who present to the emergency room. There is enthusiasm for use of BNP as a market of heart failure severity as well as a predictor of outcomes in people with heart failure and trials are ongoing. Nesiritide, a recombinant form of BNP is currently being tested as a possible treatment in people with acutely decompensated heart failure. |
| first_indexed | 2025-11-14T07:07:25Z |
| format | Journal Article |
| id | curtin-20.500.11937-14305 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:07:25Z |
| publishDate | 2009 |
| publisher | Elsevier Inc |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-143052017-09-13T15:54:08Z The role of b-type natriuretic peptide in heart failure management Newton, Phillip Betihavas, Vasiliki Macdonald, P. Heart failure peptide b-Type natriuretic Summary. Heart failure is a complex clinical syndrome that manifests itself with signs and symptoms which are neither sensitive nor specific for the diagnosis of heart failure. Natriuretic peptides and in particular b-type natriuretic peptide (and nt-proBNP) are widely used in clinical practice around the world as a maker of heart failure. BNP is primarly released from the left ventricle in response to pressure and volume overload. The strongest evidence for the use of BNP is to rule in or rule out heart failure as cause of breathlessness in people who present to the emergency room. There is enthusiasm for use of BNP as a market of heart failure severity as well as a predictor of outcomes in people with heart failure and trials are ongoing. Nesiritide, a recombinant form of BNP is currently being tested as a possible treatment in people with acutely decompensated heart failure. 2009 Journal Article http://hdl.handle.net/20.500.11937/14305 10.1016/j.aucc.2009.06.001 Elsevier Inc fulltext |
| spellingShingle | Heart failure peptide b-Type natriuretic Newton, Phillip Betihavas, Vasiliki Macdonald, P. The role of b-type natriuretic peptide in heart failure management |
| title | The role of b-type natriuretic peptide in heart failure management |
| title_full | The role of b-type natriuretic peptide in heart failure management |
| title_fullStr | The role of b-type natriuretic peptide in heart failure management |
| title_full_unstemmed | The role of b-type natriuretic peptide in heart failure management |
| title_short | The role of b-type natriuretic peptide in heart failure management |
| title_sort | role of b-type natriuretic peptide in heart failure management |
| topic | Heart failure peptide b-Type natriuretic |
| url | http://hdl.handle.net/20.500.11937/14305 |