Diagnostic accuracy of 64 multislice CT angiography in the assessment of coronary in-stent restenosis: A meta-analysis
Purpose: The aim of this study was to perform a meta-analysis of the diagnostic accuracy of 64-slice CT angiography for evaluation of coronary stent restenosis in patients treated with coronary stents when compared to conventional coronary angiography. Materials and Methods: A search of PUBMED/MEDLI...
| Main Authors: | , |
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| Format: | Journal Article |
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Elsevier Ireland Ltd
2010
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| Online Access: | http://hdl.handle.net/20.500.11937/13899 |
| _version_ | 1848748472122998784 |
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| author | Sun, Zhonghua Almutairi, Abdulrahman |
| author_facet | Sun, Zhonghua Almutairi, Abdulrahman |
| author_sort | Sun, Zhonghua |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Purpose: The aim of this study was to perform a meta-analysis of the diagnostic accuracy of 64-slice CT angiography for evaluation of coronary stent restenosis in patients treated with coronary stents when compared to conventional coronary angiography. Materials and Methods: A search of PUBMED/MEDLINE databases for English literature was performed. Only studies comparing 64-slice CT angiography with conventional coronary angiography for the detection of coronary in-stent restenosis (more than 50% stenosis) were included for analysis. Sensitivity and specificity estimates pooled across studies were tested using a fixed effects model. Fourteen studies met selection criteria for inclusion in the analysis. The mean value of assessable stents was 89%. Prevalence of in-stent restenosis following coronary stenting was 20% among these studies. Pooled estimates of the sensitivity and specificity of overall 64-slice CT angiography for the detection of coronary instent restenosis was 90% (95% CI: 86%, 94%) and 91% (95% CI: 90%, 93%), respectively, based on the evaluation of assessable stents. Diagnostic value of 64-slice CT angiography was found to decrease significantly when the analysis was performed with inclusion of nonassessable segments in five studies, with pooled sensitivity and specificity being 79% (95% CI: 68%, 88%) and 81% (95% CI: 77%, 84%). Stent diameter is the main factor affecting the diagnostic value of MSCT angiography. Conclusion: Our results showed that 64-slice CT angiography has high diagnostic value (both sensitivity and specificity) for detection of coronary in-stent restenosis based on assessable segments when compared to conventional coronary angiography. |
| first_indexed | 2025-11-14T07:05:35Z |
| format | Journal Article |
| id | curtin-20.500.11937-13899 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:05:35Z |
| publishDate | 2010 |
| publisher | Elsevier Ireland Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-138992019-02-19T04:26:13Z Diagnostic accuracy of 64 multislice CT angiography in the assessment of coronary in-stent restenosis: A meta-analysis Sun, Zhonghua Almutairi, Abdulrahman Purpose: The aim of this study was to perform a meta-analysis of the diagnostic accuracy of 64-slice CT angiography for evaluation of coronary stent restenosis in patients treated with coronary stents when compared to conventional coronary angiography. Materials and Methods: A search of PUBMED/MEDLINE databases for English literature was performed. Only studies comparing 64-slice CT angiography with conventional coronary angiography for the detection of coronary in-stent restenosis (more than 50% stenosis) were included for analysis. Sensitivity and specificity estimates pooled across studies were tested using a fixed effects model. Fourteen studies met selection criteria for inclusion in the analysis. The mean value of assessable stents was 89%. Prevalence of in-stent restenosis following coronary stenting was 20% among these studies. Pooled estimates of the sensitivity and specificity of overall 64-slice CT angiography for the detection of coronary instent restenosis was 90% (95% CI: 86%, 94%) and 91% (95% CI: 90%, 93%), respectively, based on the evaluation of assessable stents. Diagnostic value of 64-slice CT angiography was found to decrease significantly when the analysis was performed with inclusion of nonassessable segments in five studies, with pooled sensitivity and specificity being 79% (95% CI: 68%, 88%) and 81% (95% CI: 77%, 84%). Stent diameter is the main factor affecting the diagnostic value of MSCT angiography. Conclusion: Our results showed that 64-slice CT angiography has high diagnostic value (both sensitivity and specificity) for detection of coronary in-stent restenosis based on assessable segments when compared to conventional coronary angiography. 2010 Journal Article http://hdl.handle.net/20.500.11937/13899 10.1016/j.ejrad.2008.10.025 Elsevier Ireland Ltd fulltext |
| spellingShingle | Sun, Zhonghua Almutairi, Abdulrahman Diagnostic accuracy of 64 multislice CT angiography in the assessment of coronary in-stent restenosis: A meta-analysis |
| title | Diagnostic accuracy of 64 multislice CT angiography in the assessment of coronary in-stent restenosis: A meta-analysis |
| title_full | Diagnostic accuracy of 64 multislice CT angiography in the assessment of coronary in-stent restenosis: A meta-analysis |
| title_fullStr | Diagnostic accuracy of 64 multislice CT angiography in the assessment of coronary in-stent restenosis: A meta-analysis |
| title_full_unstemmed | Diagnostic accuracy of 64 multislice CT angiography in the assessment of coronary in-stent restenosis: A meta-analysis |
| title_short | Diagnostic accuracy of 64 multislice CT angiography in the assessment of coronary in-stent restenosis: A meta-analysis |
| title_sort | diagnostic accuracy of 64 multislice ct angiography in the assessment of coronary in-stent restenosis: a meta-analysis |
| url | http://hdl.handle.net/20.500.11937/13899 |