Obstructive sleep apnoea: From pathogenesis to treatment: Current controversies and future directions

Obstructive sleep apnoea (OSA) is a common disease, recognized as an independent risk factor for a range of clinical conditions, such as hypertension, stroke, depression and diabetes. Despite extensive research over the past two decades, the mechanistic links between OSA and other associated clinica...

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Main Authors: Eastwood, Peter, Malhotra, A., Palmer, L., Kezirian, E., Horner, R., Ip, M., Thurnheer, R., Antic, N., Hillman, D.
Format: Journal Article
Published: Wiley-Blackwell Publishing Asia 2010
Online Access:http://hdl.handle.net/20.500.11937/13408
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author Eastwood, Peter
Malhotra, A.
Palmer, L.
Kezirian, E.
Horner, R.
Ip, M.
Thurnheer, R.
Antic, N.
Hillman, D.
author_facet Eastwood, Peter
Malhotra, A.
Palmer, L.
Kezirian, E.
Horner, R.
Ip, M.
Thurnheer, R.
Antic, N.
Hillman, D.
author_sort Eastwood, Peter
building Curtin Institutional Repository
collection Online Access
description Obstructive sleep apnoea (OSA) is a common disease, recognized as an independent risk factor for a range of clinical conditions, such as hypertension, stroke, depression and diabetes. Despite extensive research over the past two decades, the mechanistic links between OSA and other associated clinical conditions, including metabolic disorders and cardiovascular disease, remain unclear. Indeed, the pathogenesis of OSA itself remains incompletely understood. This review provides opinions from a number of leading experts on issues related to OSA and its pathogenesis, interaction with anaesthesia, metabolic consequences and comorbidities, cardiovascular disease, genetics, measurement and diagnosis, surgical treatment and pharmacotherapeutic targets. © 2010 Asian Pacific Society of Respirology.
first_indexed 2025-11-14T07:03:28Z
format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T07:03:28Z
publishDate 2010
publisher Wiley-Blackwell Publishing Asia
recordtype eprints
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spelling curtin-20.500.11937-134082023-02-22T06:24:22Z Obstructive sleep apnoea: From pathogenesis to treatment: Current controversies and future directions Eastwood, Peter Malhotra, A. Palmer, L. Kezirian, E. Horner, R. Ip, M. Thurnheer, R. Antic, N. Hillman, D. Obstructive sleep apnoea (OSA) is a common disease, recognized as an independent risk factor for a range of clinical conditions, such as hypertension, stroke, depression and diabetes. Despite extensive research over the past two decades, the mechanistic links between OSA and other associated clinical conditions, including metabolic disorders and cardiovascular disease, remain unclear. Indeed, the pathogenesis of OSA itself remains incompletely understood. This review provides opinions from a number of leading experts on issues related to OSA and its pathogenesis, interaction with anaesthesia, metabolic consequences and comorbidities, cardiovascular disease, genetics, measurement and diagnosis, surgical treatment and pharmacotherapeutic targets. © 2010 Asian Pacific Society of Respirology. 2010 Journal Article http://hdl.handle.net/20.500.11937/13408 10.1111/j.1440-1843.2009.01699.x Wiley-Blackwell Publishing Asia unknown
spellingShingle Eastwood, Peter
Malhotra, A.
Palmer, L.
Kezirian, E.
Horner, R.
Ip, M.
Thurnheer, R.
Antic, N.
Hillman, D.
Obstructive sleep apnoea: From pathogenesis to treatment: Current controversies and future directions
title Obstructive sleep apnoea: From pathogenesis to treatment: Current controversies and future directions
title_full Obstructive sleep apnoea: From pathogenesis to treatment: Current controversies and future directions
title_fullStr Obstructive sleep apnoea: From pathogenesis to treatment: Current controversies and future directions
title_full_unstemmed Obstructive sleep apnoea: From pathogenesis to treatment: Current controversies and future directions
title_short Obstructive sleep apnoea: From pathogenesis to treatment: Current controversies and future directions
title_sort obstructive sleep apnoea: from pathogenesis to treatment: current controversies and future directions
url http://hdl.handle.net/20.500.11937/13408