The effect of cell culture on X chromosome mosaicism
The effects of cell culture on X chromosome aneuploidy in young women with established fertility were investigated. Fluorescence in situ hybridisation was performed on paired samples of mitogen stimulated and uncultured lymphocytes using probes for the X and 9 chromosomes. All participants had <...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
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Curtin University
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/134 |
| _version_ | 1848743293037314048 |
|---|---|
| author | Patton, Kirralee Anne |
| author_facet | Patton, Kirralee Anne |
| author_sort | Patton, Kirralee Anne |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The effects of cell culture on X chromosome aneuploidy in young women with established fertility were investigated. Fluorescence in situ hybridisation was performed on paired samples of mitogen stimulated and uncultured lymphocytes using probes for the X and 9 chromosomes. All participants had <5% X aneuploidy in both preparations. X chromosome loss occurred more frequently than gain. These results provide important information when interpreting the low levels of X mosaicism seen in routine cytogenetic practice. |
| first_indexed | 2025-11-14T05:43:16Z |
| format | Thesis |
| id | curtin-20.500.11937-134 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:43:16Z |
| publishDate | 2013 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-1342017-02-20T06:42:40Z The effect of cell culture on X chromosome mosaicism Patton, Kirralee Anne The effects of cell culture on X chromosome aneuploidy in young women with established fertility were investigated. Fluorescence in situ hybridisation was performed on paired samples of mitogen stimulated and uncultured lymphocytes using probes for the X and 9 chromosomes. All participants had <5% X aneuploidy in both preparations. X chromosome loss occurred more frequently than gain. These results provide important information when interpreting the low levels of X mosaicism seen in routine cytogenetic practice. 2013 Thesis http://hdl.handle.net/20.500.11937/134 en Curtin University fulltext |
| spellingShingle | Patton, Kirralee Anne The effect of cell culture on X chromosome mosaicism |
| title | The effect of cell culture on X chromosome mosaicism |
| title_full | The effect of cell culture on X chromosome mosaicism |
| title_fullStr | The effect of cell culture on X chromosome mosaicism |
| title_full_unstemmed | The effect of cell culture on X chromosome mosaicism |
| title_short | The effect of cell culture on X chromosome mosaicism |
| title_sort | effect of cell culture on x chromosome mosaicism |
| url | http://hdl.handle.net/20.500.11937/134 |