Accomplishments and challenges of protein ontology

Recent progress in proteomics, computational biology, and ontology development has presented an opportunity to investigate protein data sources from unique perspective that is, examining protein data sources through structure and hierarchy of Protein Ontology (PO). Various data mining algorithms and...

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Main Authors: Sidhu, Amandeep, Dillon, Tharam S., Hussain, Farookh Khadeer, Chang, Elizabeth
Other Authors: Ceballos, S.
Format: Conference Paper
Published: IEEE Computer Society 2006
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/13261
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author Sidhu, Amandeep
Dillon, Tharam S.
Hussain, Farookh Khadeer
Chang, Elizabeth
author2 Ceballos, S.
author_facet Ceballos, S.
Sidhu, Amandeep
Dillon, Tharam S.
Hussain, Farookh Khadeer
Chang, Elizabeth
author_sort Sidhu, Amandeep
building Curtin Institutional Repository
collection Online Access
description Recent progress in proteomics, computational biology, and ontology development has presented an opportunity to investigate protein data sources from unique perspective that is, examining protein data sources through structure and hierarchy of Protein Ontology (PO). Various data mining algorithms and mathematical models provide methods for analysing protein data sources; however, there are two issues that need to be addressed: (1) the need for standards for defining protein data description and exchange and (2) eliminating errors which arise with the data integration methodologies for complex queries. Protein Ontology is designed to meet these needs by providing a structured protein data specification for Protein Data Representation. Protein Ontology is standard for representing protein data in a way that helps in defining data integration and data mining models for Protein Structure and Function. We report here our development of PO; a semantic heterogeneity framework based on relationships between PO concepts; and analysis of resultant PO Data of Human Proteins. We also talk in this paper briefly about our ongoing work of designing a trustworthy framework around PO.
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spelling curtin-20.500.11937-132612017-09-13T16:01:59Z Accomplishments and challenges of protein ontology Sidhu, Amandeep Dillon, Tharam S. Hussain, Farookh Khadeer Chang, Elizabeth Ceballos, S. data mining protein ontology ontologies trustworthy ontology protein data source Recent progress in proteomics, computational biology, and ontology development has presented an opportunity to investigate protein data sources from unique perspective that is, examining protein data sources through structure and hierarchy of Protein Ontology (PO). Various data mining algorithms and mathematical models provide methods for analysing protein data sources; however, there are two issues that need to be addressed: (1) the need for standards for defining protein data description and exchange and (2) eliminating errors which arise with the data integration methodologies for complex queries. Protein Ontology is designed to meet these needs by providing a structured protein data specification for Protein Data Representation. Protein Ontology is standard for representing protein data in a way that helps in defining data integration and data mining models for Protein Structure and Function. We report here our development of PO; a semantic heterogeneity framework based on relationships between PO concepts; and analysis of resultant PO Data of Human Proteins. We also talk in this paper briefly about our ongoing work of designing a trustworthy framework around PO. 2006 Conference Paper http://hdl.handle.net/20.500.11937/13261 10.1109/COMPSAC.2006.18 IEEE Computer Society fulltext
spellingShingle data mining
protein ontology
ontologies
trustworthy
ontology
protein data source
Sidhu, Amandeep
Dillon, Tharam S.
Hussain, Farookh Khadeer
Chang, Elizabeth
Accomplishments and challenges of protein ontology
title Accomplishments and challenges of protein ontology
title_full Accomplishments and challenges of protein ontology
title_fullStr Accomplishments and challenges of protein ontology
title_full_unstemmed Accomplishments and challenges of protein ontology
title_short Accomplishments and challenges of protein ontology
title_sort accomplishments and challenges of protein ontology
topic data mining
protein ontology
ontologies
trustworthy
ontology
protein data source
url http://hdl.handle.net/20.500.11937/13261