Novel roles for class II Phosphoinositide 3-Kinase C2ß in signalling pathways involved in prostate cancer cell invasion.

QR Code

Novel roles for class II Phosphoinositide 3-Kinase C2ß in signalling pathways involved in prostate cancer cell invasion.

Phosphoinositide 3-kinases (PI3Ks) regulate several cellular functions such as proliferation, growth, survival and migration. The eight PI3K isoforms are grouped into three classes and the three enzymes belonging to the class II subfamily (PI3K-C2a, ß and ?) are the least investigated amongst all PI...

Full description

Bibliographic Details
Main Authors:	Mavrommati, I., Cisse, O., Falasca, Marco, Maffucci, T.
Format:	Journal Article
Published:	Nature Publishing Group 2016
Online Access:	http://hdl.handle.net/20.500.11937/13051

Similar Items

Class II phosphoinositide 3-kinase C2ß regulates a novel signaling pathway involved in breast cancer progression.
by: Chikh, A., et al.
Published: (2016)

Regulation and cellular functions of class II phosphoinositide 3-kinases
by: Falasca, Marco, et al.
Published: (2012)

New insight into the intracellular roles of class II phosphoinositide 3-kinases
by: Maffucci, T., et al.
Published: (2014)

Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
by: Tibolla, G., et al.
Published: (2013)

Phosphoinositide 3-kinase pathway inhibitors: pharmacology, metabolism & drug development
by: Falasca, Marco
Published: (2011)

Investigating the mechanisms of activation and action of phosphoinositide 3-kinase C2 alpha in pancreatic beta cells
by: Mazza, S., et al.
Published: (2013)

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic ß cells
by: Dominguez, V., et al.
Published: (2011)

Targeting phosphoinositide 3-kinase pathways in pancreatic cancer - from molecular signalling to clinical trials
by: Falasca, Marco, et al.
Published: (2011)

Key role of phosphoinositide 3-kinase class IB in pancreatic cancer
by: Edling, C., et al.
Published: (2010)

Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway
by: Edling, C., et al.
Published: (2014)

Class II Phosphoinositide 3-Kinases as Novel Drug Targets
by: Falasca, Marco, et al.
Published: (2017)

Analysis, regulation, and roles of endosomal phosphoinositides
by: Maffucci, T., et al.
Published: (2014)

Genetic and epigenetic regulation of phosphoinositide 3-kinase isoforms
by: Fyffe, C., et al.
Published: (2013)

A phosphoinositide 3-kinase/phospholipase cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation
by: Maffucci, T., et al.
Published: (2009)

3-phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
by: Fyffe, C., et al.
Published: (2013)

THE CLASS II PHOSPHOINOSITIDE 3-KINASE ISOFORM beta REGULATES PLATELET FUNCTION AND ARTERIAL THROMBOSIS IN MICE
by: Tibolla, G., et al.
Published: (2011)

Elucidation of the WNT & AKT/Phosphoinositide-3-Kinase Pathways in Colorectal Carcinoma
by: Khor, Tin Oo
Published: (2004)

Phosphoinositides signalling in cancer: Focus on PI3K and PLC
by: Raimondi, C., et al.
Published: (2012)

Role and regulation of phosphatidylinositol 3-kinase ß in platelet integrin α2ß1 signaling
by: Consonni, A., et al.
Published: (2012)

Cudraflavone C induces tumor-specific apoptosis in colorectal cancer cells through inhibition of the phosphoinositide 3-kinase (PI3K)-AKT pathway
by: Castresana, Javier S., et al.
Published: (2017)

Activation of phosphatidylinositol 3-kinase ß by the platelet collagen receptors integrin a2ß1 and GPVI: The role of Pyk2 and c-Cbl
by: Manganaro, D., et al.
Published: (2015)

Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer
by: Zhang, J., et al.
Published: (2017)

Role of phospholipase C in cell invasion and metastasis
by: Lattanzio, R., et al.
Published: (2013)

PITPs as targets for selectively interfering with phosphoinositide signaling in cells
by: Nile, A., et al.
Published: (2014)

The extracellular signal-regulated kinase (ERK) pathway: a potential therapeutic target in hypertension
by: Roberts, Richard E.
Published: (2012)

The Mak2 MAP kinase signal transduction pathway is required for pathogenicity in Stagonospora nodorum
by: Solomon, P., et al.
Published: (2005)

Src family tyrosine kinase Lyn mediates VWF GPIb-IX induced platelet activation via the cGMP signaling pathway
by: Yin, H., et al.
Published: (2008)

Identification and characterization of micrornas involved in the invasion and migration properties of lung, prostate and breast cancer cells / Yap Seow Hui
by: Yap, Seow Hui
Published: (2012)

The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets
by: Canobbio, I., et al.
Published: (2015)

Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts
by: Falasca, Marco, et al.
Published: (2014)

Rethinking phosphatidylinositol 3-monophosphate
by: Falasca, Marco, et al.
Published: (2009)

Akt/protein kinase B in skeletal muscle physiology and pathology
by: Wu, M., et al.
Published: (2011)

Phospholipase C-beta 4 regulates proliferation and invasion in cutaneous SCC
by: Ruban, E., et al.
Published: (2013)

Functional association of phosphoinositide-3-kinase with platelet glycoprotein Iba, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex
by: Mu, F., et al.
Published: (2010)

Molecular Signaling Pathways Involved in the Glucose-Lowering Effect of Teucrium polium
by: Mannan, Adnan
Published: (2017)

Phospholipase C signalling in cutaneous squamous cell carcinoma
by: Ruban, E., et al.
Published: (2011)

Phospholipase C signalling in cutaneous squamous cell carcinoma
by: Ruban, E., et al.
Published: (2011)

Phospholipase C signalling in cutaneous squamous cell carcinoma
by: Ruban, E., et al.
Published: (2012)

Phospholipase C beta4 regulates invasion and proliferation in cutaneous SCC in vivo
by: Ruban, E., et al.
Published: (2014)

Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma
by: Subramaniam, A., et al.
Published: (2012)