Peroxiredoxin III protects pancreatic ß cells from apoptosis

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Peroxiredoxin III protects pancreatic ß cells from apoptosis

Type 1 diabetes mellitus is characterized by a progressive autoimmune destruction of insulin-producing ß cells. Macrophages and T lymphocytes release cytokines, which induce the synthesis of oxygen and nitrogen radicals in the pancreatic islets. The resulting cellular and mitochondrial damage promot...

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Bibliographic Details
Main Authors:	Wolf, G., Aumann, N., Michalska, M., Bast, A., Sonnemann, J., Beck, J., Lendeckel, U., Newsholme, Philip, Walther, R.
Format:	Journal Article
Published:	BioScientifica 2010
Online Access:	http://hdl.handle.net/20.500.11937/13012

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