Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy

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Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy

Objectives: Bcl-2 is a protein that inhibits apoptosis, leading to cell survival. The Bcl-2 family has six different anti-apoptotic proteins, three pro-apoptotic proteins that are similar in structure, and other integrating proteins that function as promotors or inhibitors in the progression of apop...

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Bibliographic Details
Main Authors:	Tomek, M., Akiyama, T., Dass, Crispin
Format:	Journal Article
Published:	John Wiley & Sons Ltd. 2012
Subjects:	cell survival apoptosis Nur-77 FKBP-38 Bcl-2 cancer
Online Access:	http://hdl.handle.net/20.500.11937/12828

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