Target DNA recognition using electrochemical impedance spectroscopy
Electrochemical impedance spectroscopy was used to differentiate between different target DNA sequences without the use of a redox label or application of large bias voltages. This method relies on the formation of a mixed self-assembled monolayer (SAMs) composed of single-stranded DNA and a diluent...
| Main Authors: | , , , |
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| Format: | Conference Paper |
| Published: |
2010
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| Online Access: | http://hdl.handle.net/20.500.11937/12630 |
| _version_ | 1848748129300512768 |
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| author | Michaels, P. Ciampi, Simone Yean, C. Gooding, J. |
| author_facet | Michaels, P. Ciampi, Simone Yean, C. Gooding, J. |
| author_sort | Michaels, P. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Electrochemical impedance spectroscopy was used to differentiate between different target DNA sequences without the use of a redox label or application of large bias voltages. This method relies on the formation of a mixed self-assembled monolayer (SAMs) composed of single-stranded DNA and a diluent, mercaptoethanol. Recognition of the DNA analytes was achieved through the significant increase in conductance for the double stranded DNA, as compared to single-stranded DNA. Non-complementary and single base-pair mismatches were also able to be differentiated. © 2010 IEEE. |
| first_indexed | 2025-11-14T07:00:08Z |
| format | Conference Paper |
| id | curtin-20.500.11937-12630 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:00:08Z |
| publishDate | 2010 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-126302018-03-29T09:05:58Z Target DNA recognition using electrochemical impedance spectroscopy Michaels, P. Ciampi, Simone Yean, C. Gooding, J. Electrochemical impedance spectroscopy was used to differentiate between different target DNA sequences without the use of a redox label or application of large bias voltages. This method relies on the formation of a mixed self-assembled monolayer (SAMs) composed of single-stranded DNA and a diluent, mercaptoethanol. Recognition of the DNA analytes was achieved through the significant increase in conductance for the double stranded DNA, as compared to single-stranded DNA. Non-complementary and single base-pair mismatches were also able to be differentiated. © 2010 IEEE. 2010 Conference Paper http://hdl.handle.net/20.500.11937/12630 10.1109/ICONN.2010.6045241 restricted |
| spellingShingle | Michaels, P. Ciampi, Simone Yean, C. Gooding, J. Target DNA recognition using electrochemical impedance spectroscopy |
| title | Target DNA recognition using electrochemical impedance spectroscopy |
| title_full | Target DNA recognition using electrochemical impedance spectroscopy |
| title_fullStr | Target DNA recognition using electrochemical impedance spectroscopy |
| title_full_unstemmed | Target DNA recognition using electrochemical impedance spectroscopy |
| title_short | Target DNA recognition using electrochemical impedance spectroscopy |
| title_sort | target dna recognition using electrochemical impedance spectroscopy |
| url | http://hdl.handle.net/20.500.11937/12630 |