Artemisinin-Naphthoquine versus Artemether-Lumefantrine for Uncomplicated Malaria in Papua New Guinean Children: An Open-Label Randomized Trial

QR Code

Artemisinin-Naphthoquine versus Artemether-Lumefantrine for Uncomplicated Malaria in Papua New Guinean Children: An Open-Label Randomized Trial

© 2014 Laman et al. Artemisinin combination therapies (ACTs) with broad efficacy are needed where multiple Plasmodium species are transmitted, especially in children, who bear the brunt of infection in endemic areas. In Papua New Guinea (PNG), artemether-lumefantrine is the first-line treatment for...

Full description

Bibliographic Details
Main Authors:	Laman, M., Moore, Brioni, Benjamin, J., Yadi, G., Bona, C., Warrel, J., Kattenberg, J., Koleala, T., Manning, L., Kasian, B., Robinson, L., Sambale, N., Lorry, L., Karl, S., Davis, W., Rosanas-Urgell, A., Mueller, I., Siba, P., Betuela, I., Davis, T.
Format:	Journal Article
Published:	Public Library of Science 2014
Online Access:	http://hdl.handle.net/20.500.11937/12365

Similar Items

Cost-effectiveness of artemisinin-naphthoquine versus artemether-lumefantrine for the treatment of uncomplicated malaria in Papua New Guinean children
by: Moore, Brioni, et al.
Published: (2017)

Artemether-lumefantrine versus artemisinin-naphthoquine in Papua New Guinean children with uncomplicated malaria: A six months post-treatment follow-up study
by: Laman, M., et al.
Published: (2015)

Population Pharmacokinetics of Artemether, Lumefantrine, and Their Respective Metabolites in Papua New Guinean Children with Uncomplicated Malaria
by: Salman, S., et al.
Published: (2011)

Meningeal inflammation increases cerebrospinal fluid artemether concentrations in Papua New Guinean children treated with intramuscular artemether
by: Manning, L., et al.
Published: (2011)

Risk factors for Plasmodium falciparum and Plasmodium vivax gametocyte carriage in Papua New Guinean children with uncomplicated malaria
by: Karl, S., et al.
Published: (2016)

Artemisinin-Naphthoquine Combination Therapy for Uncomplicated Pediatric Malaria: a Pharmacokinetic Study
by: Batty, Kevin, et al.
Published: (2012)

The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children
by: Sugiarto, S.R., et al.
Published: (2022)

Artemisinin-naphthoquine combination therapy for uncomplicated pediatric malaria: A tolerability, safety, and preliminary efficacy study
by: Benjamin, J., et al.
Published: (2012)

Comparison of an assumed versus measured leucocyte count in parasite density calculations in Papua New Guinean children with uncomplicated malaria
by: Laman, M., et al.
Published: (2014)

Naphthoquine: An Emerging Candidate for Artemisinin Combination Therapy
by: Moore, Brioni, et al.
Published: (2016)

Comparative safety of artemether-lumefantrine and other artemisinin-based combinations in children: a systematic review
by: Egunsola, Oluwaseun, et al.
Published: (2013)

Comparison of three methods for detection of gametocytes in Melanesian children treated for uncomplicated malaria
by: Karl, S., et al.
Published: (2014)

Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria
by: Salman, S., et al.
Published: (2012)

Gametocyte clearance kinetics determined by quantitative magnetic fractionation in Melanesian children with uncomplicated malaria treated with artemisinin combination therapy
by: Karl, S., et al.
Published: (2015)

Effect of coadministered fat on the tolerability, safety and pharmacokinetic properties of dihydroartemisinin-piperaquine in Papua New Guinean children with uncomplicated malaria
by: Moore, Brioni, et al.
Published: (2014)

Temporal changes in Plasmodium falciparum anti-malarial drug sensitivity in vitro and resistance-associated genetic mutations in isolates from Papua New Guinea
by: Koleala, T., et al.
Published: (2015)

Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women
by: Benjamin, J., et al.
Published: (2015)

PHARMACOKINETICS OF TRANSFER OF PIPERAQUINE INTO THE BREAST MILK OF PAPUA NEW GUINEAN MOTHERS
by: Moore, B., et al.
Published: (2015)

Safety, tolerability and pharmacokinetic properties of coadministered azithromycin and piperaquine in pregnant Papua New Guinean women
by: Moore, B., et al.
Published: (2016)

Validation of a dried blood spot ceftriaxone assay in Papua New Guinean children with severe bacterial infections
by: Mukap, M., et al.
Published: (2018)

Pharmacokinetic properties of single-dose primaquine in Papua New Guinean children: Feasibility of abbreviated high-dose regimens for radical cure of vivax malaria
by: Moore, Brioni, et al.
Published: (2014)

Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria
by: Karunajeewa, H., et al.
Published: (2008)

Oxytocin versus carbetocin administered to cows after uncomplicated calvings and subsequent fertility
by: Robinson, N.J., et al.
Published: (2016)

Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections
by: Daneshvar, C., et al.
Published: (2010)

Liver injury in uncomplicated malaria: an overlooked phenomenon.
by: Moore, Brioni
Published: (2018)

Pharmacoeconomic analysis of uncomplicated hypertension in ambulatory care clinic.
by: Qais, Mohammad Ahmad Al-Efan
Published: (2011)

Artemisinin therapy for malaria in hemoglobinopathies: A systematic review
by: Sugiarto, S., et al.
Published: (2018)

Contemporary review of risk-stratified management in acute uncomplicated and complicated diverticulitis
by: Boermeester, Marja A., et al.
Published: (2016)

Development of a Papua New Guinean onshore carbonate reservoir: A comparative borehole image (FMI) and petrographic evaluation
by: Wilson, Moyra, et al.
Published: (2013)

Methicillin-resistant Staphylococcus aureus in Papua New Guinea: A community nasal colonization prevalence study
by: Laman, M., et al.
Published: (2017)

Anti-inflammatory and antibacterial effects of kinos from Australian and Papua New Guinean Eucalyptus species
by: Mungkaje, Martha Yahimbu
Published: (2015)

Emerging possibilities and constraints to Papua New Guinean smallholder coffee producers entering the speciality coffee market
by: Murray-Prior, Roy, et al.
Published: (2007)

Investigation of the binding characteristics of anti-malarial drugs, mefloquine, lumefantrine and pyrimethamine to human serum albumin using spectroscopic and molecular docking methods / Kabiru Abubakar Musa
by: Kabiru , Abubakar Musa
Published: (2021)

An evaluation of patients’ adherence with hypoglycemic medications among Papua New Guineans with Type 2 Diabetes: Influencing factors
by: Pihau-Tulo, Stella, et al.
Published: (2014)

Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled Trial
by: Pomat, William, et al.
Published: (2013)

External cephalic version as a primary option in the management of uncomplicated singleton term breech pregnancy: is it worthwhile?
by: Sachlin, Mimin Tarmini
Published: (2002)

Factors associated with uncomplicated prolonged neonatal jaundice in term Malay infants : a case control study
by: Zahedi, Nor Amirah Ahmad
Published: (2020)

Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay
by: Page-Sharp, Madhu, et al.
Published: (2012)

Safety and efficacy of antibiotics compared with appendicectomy for treatment of uncomplicated acute appendicitis: meta-analysis of randomised controlled trials
by: Varadhan, Krishna K., et al.
Published: (2012)

Quality of antimalarial drugs and antibiotics in Papua New Guinea: A survey of the health facility supply chain
by: Hetzel, M., et al.
Published: (2014)

Cannot write session to /tmp/vufind_sessions/sess_sqvgcob8cd2j01eqoe283ju5ph