Pigment epithelium-derived factor as an anticancer drug and new treatment methods following the discovery of its receptors: a patent perspective
Traditional forms of cancer therapy, which include chemotherapy, have largely been overhauled due to the significant degree of toxicity they pose to normal, otherwise healthy tissue. It is hoped that the use of biological agents, most of which are endogenously present in the body, will lead to safer...
| Main Authors: | Manalo, K., Choong, P., Becerra, S., Dass, Crispin |
|---|---|
| Format: | Journal Article |
| Published: |
Informa Healthcare
2011
|
| Online Access: | http://hdl.handle.net/20.500.11937/12326 |
Similar Items
Pigment Epithelium-Derived Factor: Chemistry, Structure, Biology, and Applications
by: Becerra, S.P., et al.
Published: (2012)
by: Becerra, S.P., et al.
Published: (2012)
Pigment Epithelium-Derived Factor as an Impending Therapeutic Agent Against Vascular Epithelial Growth Factor-Driven Tumor-Angiogenesis
by: Manalo, K., et al.
Published: (2011)
by: Manalo, K., et al.
Published: (2011)
Potential of pigment epithelium-derived factor (PEDF) as a bone regenerative biopharmaceutical
by: Lee, P., et al.
Published: (2016)
by: Lee, P., et al.
Published: (2016)
Stimulation of bone regeneration with pigment epithelium-derived factor microparticles: Evidence in silico, in vitro and in vivo
by: Lee, P., et al.
Published: (2016)
by: Lee, P., et al.
Published: (2016)
Pigment epithelium-derived factor: a key mediator in bone homeostasis and potential for bone regenerative therapy
by: Baxter-Holland, M., et al.
Published: (2018)
by: Baxter-Holland, M., et al.
Published: (2018)
Pigment epithelium-derived factor as a natural matrix metalloproteinase inhibitor: a comparison with classical matrix metalloproteinase inhibitors used for cancer treatment
by: Alcantara, M., et al.
Published: (2014)
by: Alcantara, M., et al.
Published: (2014)
Reduction in tumour cell invasion by pigment epithelium-derived factor is mediated by membrane type-1 matrix metalloproteinase downregulation
by: Filiz, G., et al.
Published: (2012)
by: Filiz, G., et al.
Published: (2012)
Insulin antagonises pigment epithelium-derived factor (PEDF)-induced modulation of lineage commitment of myocytes and heterotrophic ossification
by: Carnagarin, R., et al.
Published: (2018)
by: Carnagarin, R., et al.
Published: (2018)
Pigment epithelium-derived factor and
menopause in metastatic breast cancer
by: Brook, Naomi Louise
Published: (2022)
by: Brook, Naomi Louise
Published: (2022)
Pigment Epithelium-derived Factor and Insulin Crosstalk in Skeletal Muscle Biology
by: Carnagarin, Revathy
Published: (2017)
by: Carnagarin, Revathy
Published: (2017)
The Role of Pigment Epithelium-derived Factor in Breast
Cancer Cell Metabolism
by: Abooshahab, Raziyeh
Published: (2025)
by: Abooshahab, Raziyeh
Published: (2025)
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone
by: Alcantara, M., et al.
Published: (2014)
by: Alcantara, M., et al.
Published: (2014)
Pigment epithelium-derived factor stimulates skeletal muscle glycolytic activity through NADPH oxidase-dependent reactive oxygen species production
by: Carnagarin, R., et al.
Published: (2016)
by: Carnagarin, R., et al.
Published: (2016)
Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems
by: Tacar, O., et al.
Published: (2013)
by: Tacar, O., et al.
Published: (2013)
Treatment of lung cancer using nanoparticle drug delivery systems
by: Chandolu, V., et al.
Published: (2013)
by: Chandolu, V., et al.
Published: (2013)
Pigment epithelium-derived factor (PEDF) regulates metabolism and insulin secretion from a clonal rat pancreatic beta cell line BRIN-BD11 and mouse islets
by: Chen, Y., et al.
Published: (2016)
by: Chen, Y., et al.
Published: (2016)
Bone drug targets
by: Dass, Crispin
Published: (2018)
by: Dass, Crispin
Published: (2018)
SAO extraction on patent discovery system development for Islamic finance and banking
by: Othman, Roslina, et al.
Published: (2016)
by: Othman, Roslina, et al.
Published: (2016)
Patented and Generic Pharmaceutical Drugs: Perception and Prescription
by: Ernest Cyril, de Run, et al.
Published: (2006)
by: Ernest Cyril, de Run, et al.
Published: (2006)
Drug delivery in cancer using liposomes
by: Dass, Crispin
Published: (2008)
by: Dass, Crispin
Published: (2008)
P2X purinergic receptor ligands: recently patented compounds
by: Gunosewoyo, Hendra, et al.
Published: (2010)
by: Gunosewoyo, Hendra, et al.
Published: (2010)
The applied biochemistry of PEDF and implications for tissue homeostasis
by: Broadhead, M., et al.
Published: (2010)
by: Broadhead, M., et al.
Published: (2010)
Mesoporous silica nanoparticles as anticancer drug carriers in pancreatic cancer treatment
by: Chung, Shei Li
Published: (2025)
by: Chung, Shei Li
Published: (2025)
Thiolated pectin–doxorubicin conjugates: Synthesis, characterization and anticancer activity studies
by: Cheewatanakornkool, K., et al.
Published: (2017)
by: Cheewatanakornkool, K., et al.
Published: (2017)
Efficacy of Continuously Administered PEDF-Derived Synthetic Peptides against Osteosarcoma Growth and Metastasis
by: Broadhead, M., et al.
Published: (2012)
by: Broadhead, M., et al.
Published: (2012)
In vivo evaluation of anticancer efficacy of drug loaded cockle shell‐derived aragonite nanoparticles
by: Fu, Wenliang, et al.
Published: (2019)
by: Fu, Wenliang, et al.
Published: (2019)
Finding chemo: the search for marine-based pharmaceutical drugs active against cancer
by: Indumathy, S., et al.
Published: (2013)
by: Indumathy, S., et al.
Published: (2013)
Automotive technology and patent assignee in Malaysia: an exploratory patent
by: Harun, Aizul Nahar, et al.
Published: (2023)
by: Harun, Aizul Nahar, et al.
Published: (2023)
Patent search
by: Othman, Roslina, et al.
Published: (2011)
by: Othman, Roslina, et al.
Published: (2011)
Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo
by: Flanagan, D., et al.
Published: (2017)
by: Flanagan, D., et al.
Published: (2017)
Biodegradable drug delivery systems for cancer therapy
by: Wong, T., et al.
Published: (2017)
by: Wong, T., et al.
Published: (2017)
Discovery Of Peroxisome
Proliferator-Activated Receptor
Gamma Agonist
by: Lee, Guan Sheng
Published: (2013)
by: Lee, Guan Sheng
Published: (2013)
Kinase targets in CNS drug discovery
by: Gunosewoyo, Hendra, et al.
Published: (2017)
by: Gunosewoyo, Hendra, et al.
Published: (2017)
The importance of in-silico studies in drug discovery
by: Roney, Miah, et al.
Published: (2024)
by: Roney, Miah, et al.
Published: (2024)
The evolutionary development in drug discovery and delivery
by: Ithnin, Hairuszah, et al.
Published: (2013)
by: Ithnin, Hairuszah, et al.
Published: (2013)
A study on patent protection and access to affordable drugs /Adelia Adnan…[et al.]
by: Adnan, Adelia, et al.
Published: (2011)
by: Adnan, Adelia, et al.
Published: (2011)
Patents and the Agricultural Industry
by: Sadler, Pauline
Published: (2007)
by: Sadler, Pauline
Published: (2007)
Transdifferentiation of adipocytes to osteoblasts: potential for orthopaedic treatment
by: Lin, D., et al.
Published: (2018)
by: Lin, D., et al.
Published: (2018)
Discovery of fevipiprant (NVP-QAW039), a potent and selective DP2 receptor antagonist for treatment of asthma
by: Sandham, David A., et al.
Published: (2017)
by: Sandham, David A., et al.
Published: (2017)
Intrinsic Differences Of Epithelial Tight Junctions In Asthmatic Airway Epithelium And Barrier Compromisation Following Human Rhinoviral Insult
by: Looi, K., et al.
Published: (2015)
by: Looi, K., et al.
Published: (2015)
Similar Items
-
Pigment Epithelium-Derived Factor: Chemistry, Structure, Biology, and Applications
by: Becerra, S.P., et al.
Published: (2012) -
Pigment Epithelium-Derived Factor as an Impending Therapeutic Agent Against Vascular Epithelial Growth Factor-Driven Tumor-Angiogenesis
by: Manalo, K., et al.
Published: (2011) -
Potential of pigment epithelium-derived factor (PEDF) as a bone regenerative biopharmaceutical
by: Lee, P., et al.
Published: (2016) -
Stimulation of bone regeneration with pigment epithelium-derived factor microparticles: Evidence in silico, in vitro and in vivo
by: Lee, P., et al.
Published: (2016) -
Pigment epithelium-derived factor: a key mediator in bone homeostasis and potential for bone regenerative therapy
by: Baxter-Holland, M., et al.
Published: (2018)