Activation of Survival and Apoptotic Signaling Pathways in Lymphocytes Exposed to Palmitic Acid

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Activation of Survival and Apoptotic Signaling Pathways in Lymphocytes Exposed to Palmitic Acid

The toxicity of palmitic acid (PA) towards a human T-lymphocyte cell line (Jurkat) has been previously investigated but the mechanism(s) of PA action were unknown. In the current study, Jurkat cells were treated with sub-lethal concentrations of PA (50–150µM) and the activity of various signaling pr...

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Bibliographic Details
Main Authors:	Takahashi, H., Cambiaghi, T., Luchessi, A., Hirabara, S., Vinolo, M., Newsholme, Philip, Curi, R.
Format:	Journal Article
Published:	Wiley-Liss.Inc 2011
Subjects:	Apoptosis Palmitic Acid Jurkat Cells Cell Metabolism Cell Survival
Online Access:	http://hdl.handle.net/20.500.11937/12222

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