Topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis
Chronic pain in knee osteoarthritis may develop as a result of centrally-augmented pain processing. Cold hyperalgesia has been proposed as a key indicator but is problematic to assess. A new topical menthol test was developed. It demonstrated reliability and sensitivity to discriminate between those...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
Curtin University
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/1207 |
| _version_ | 1848743601708728320 |
|---|---|
| author | Moss, Penny |
| author_facet | Moss, Penny |
| author_sort | Moss, Penny |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Chronic pain in knee osteoarthritis may develop as a result of centrally-augmented pain processing. Cold hyperalgesia has been proposed as a key indicator but is problematic to assess. A new topical menthol test was developed. It demonstrated reliability and sensitivity to discriminate between those with normal and abnormal cold pain thresholds in healthy cohorts. In knee osteoarthritis, high menthol test score was associated with greater pain and disability, widespread mechanical hyperalgesia and higher PainDETECT score. |
| first_indexed | 2025-11-14T05:48:10Z |
| format | Thesis |
| id | curtin-20.500.11937-1207 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:48:10Z |
| publishDate | 2013 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-12072017-02-20T06:39:26Z Topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis Moss, Penny Chronic pain in knee osteoarthritis may develop as a result of centrally-augmented pain processing. Cold hyperalgesia has been proposed as a key indicator but is problematic to assess. A new topical menthol test was developed. It demonstrated reliability and sensitivity to discriminate between those with normal and abnormal cold pain thresholds in healthy cohorts. In knee osteoarthritis, high menthol test score was associated with greater pain and disability, widespread mechanical hyperalgesia and higher PainDETECT score. 2013 Thesis http://hdl.handle.net/20.500.11937/1207 en Curtin University fulltext |
| spellingShingle | Moss, Penny Topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis |
| title | Topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis |
| title_full | Topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis |
| title_fullStr | Topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis |
| title_full_unstemmed | Topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis |
| title_short | Topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis |
| title_sort | topical menthol identifies cold hyperalgesia in individuals with chronic pain from knee osteoarthritis |
| url | http://hdl.handle.net/20.500.11937/1207 |