Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice.
Aims of the research:To characterise the tissue histology and tissue distribution patterns of C. albicans during systemic murine candidiasis.To develop a reliable, reproducible and sensitive SQ-RT-PCR for the quantitation of in vivo cytokine gene transcription.To use this technique to determine the...
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| Format: | Thesis |
| Language: | English |
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Curtin University
1997
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| Online Access: | http://hdl.handle.net/20.500.11937/1182 |
| _version_ | 1848743594644471808 |
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| author | Redwood, Alec J. |
| author_facet | Redwood, Alec J. |
| author_sort | Redwood, Alec J. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Aims of the research:To characterise the tissue histology and tissue distribution patterns of C. albicans during systemic murine candidiasis.To develop a reliable, reproducible and sensitive SQ-RT-PCR for the quantitation of in vivo cytokine gene transcription.To use this technique to determine the in vivo pattern of tissue specific cytokine gene expression during systemic candidiasis.To determine if cytokine gene expression patterns vary between resistant BALB/c and sensitive CBA/CaH mice during primary systemic candidiasis.To determine if differences in tissue distribution of C. albicans in infected mice is matched by differences in tissue responses to infection.To determine if cytokine mRNA expression patterns during secondary systemic candidiasis, are different to those during primary systemic candidiasis.To determine if cytokine gene expression patterns vary between resistant BALB/c and sensitive CBA/CaH mice during secondary systemic candidiasis. |
| first_indexed | 2025-11-14T05:48:03Z |
| format | Thesis |
| id | curtin-20.500.11937-1182 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:48:03Z |
| publishDate | 1997 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-11822017-02-20T06:39:51Z Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice. Redwood, Alec J. cytokines immune response Candida albicans Aims of the research:To characterise the tissue histology and tissue distribution patterns of C. albicans during systemic murine candidiasis.To develop a reliable, reproducible and sensitive SQ-RT-PCR for the quantitation of in vivo cytokine gene transcription.To use this technique to determine the in vivo pattern of tissue specific cytokine gene expression during systemic candidiasis.To determine if cytokine gene expression patterns vary between resistant BALB/c and sensitive CBA/CaH mice during primary systemic candidiasis.To determine if differences in tissue distribution of C. albicans in infected mice is matched by differences in tissue responses to infection.To determine if cytokine mRNA expression patterns during secondary systemic candidiasis, are different to those during primary systemic candidiasis.To determine if cytokine gene expression patterns vary between resistant BALB/c and sensitive CBA/CaH mice during secondary systemic candidiasis. 1997 Thesis http://hdl.handle.net/20.500.11937/1182 en Curtin University fulltext |
| spellingShingle | cytokines immune response Candida albicans Redwood, Alec J. Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice. |
| title | Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice. |
| title_full | Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice. |
| title_fullStr | Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice. |
| title_full_unstemmed | Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice. |
| title_short | Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice. |
| title_sort | cytokine gene expression patterns and immune responses to systemic candida albicans infection in inbred mice. |
| topic | cytokines immune response Candida albicans |
| url | http://hdl.handle.net/20.500.11937/1182 |