Hepatic iron loading in mice increases cholesterol biosynthesis

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Hepatic iron loading in mice increases cholesterol biosynthesis

Iron and cholesterol are both essential metabolites in mammalian systems, and too much or too little of either can have serious clinical consequences. In addition, both have been associated with steatosis and its progression, contributing, inter alia, to an increase in hepatic oxidative stress. The...

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Bibliographic Details
Main Authors:	Graham, Ross, Chua, A., Carter, K., Delima, R., Johnstone, D., Herbison, C., Firth, M., O'Leary, R., Milward, E., Olynyk, J., Trinder, D.
Format:	Journal Article
Published:	John Wiley & Sons Inc. 2010
Online Access:	http://hdl.handle.net/20.500.11937/11694

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