Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors
BACKGROUND: The primary purpose of this study was to determine associations of accelerometer-assessed moderate- to vigorousintensity physical activity (MVPA) and sedentary time with health-related quality of life (HRQoL) and physical function and well-being in colon cancer survivors. METHODS: Colon...
| Main Authors: | , , , |
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| Format: | Journal Article |
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John Wiley & Sons, Inc.
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/11682 |
| _version_ | 1848747870965989376 |
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| author | Vallance, J. Boyle, Terry Courneya, K. Lynch, B. |
| author_facet | Vallance, J. Boyle, Terry Courneya, K. Lynch, B. |
| author_sort | Vallance, J. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | BACKGROUND: The primary purpose of this study was to determine associations of accelerometer-assessed moderate- to vigorousintensity physical activity (MVPA) and sedentary time with health-related quality of life (HRQoL) and physical function and well-being in colon cancer survivors. METHODS: Colon cancer survivors (N=178) from Alberta, Canada (n=92) and Western Australia (n=86) completed a mailed survey that assessed HRQoL (Functional Assessment of Cancer Therapy-Colorectal), physical function and wellbeing (Trial Outcome Index-Colorectal), and relevant covariates. MVPA and sedentary time were assessed using the Actigraph GT3X1 accelerometer (60-second epochs) via a 7-day monitoring protocol. Average daily MVPA and sedentary time was corrected for wear time and then examined as quartiles. RESULTS: Adjusting for relevant demographic, behavioral, and clinical covariates, a significant difference in HRQoL scores emerged between quartile 1 (Q1) and Q4 (Mdiff=11.5, P=.038). For physical function and wellbeing, a significant difference emerged between Q1 and Q4 (Mdiff=9.1, P=.009). For fatigue, a significant difference emerged between Q1 and Q4 (Mdiff=7.1, P=.05). Significant differences were also observed for between Q1 and Q3 (Mdiff=2.4, P=.041), and Q1 and Q4 (Mdiff=3.5, P=.002) for colorectal cancer-specific symptoms. There were no statistically significant associations of sedentary time with HRQoL, physical function and well-being, fatigue, or colorectal cancer-specific symptoms. CONCLUSIONS: Objectively measured MVPA, but not sedentary time, was associated with better HRQoL, physical function and well-being, and colorectal cancer- specific symptoms in colon cancer survivors. For MVPA, differences met or exceeded contemporary cutpoints for determining clinically important differences. |
| first_indexed | 2025-11-14T06:56:01Z |
| format | Journal Article |
| id | curtin-20.500.11937-11682 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T06:56:01Z |
| publishDate | 2014 |
| publisher | John Wiley & Sons, Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-116822017-09-13T14:57:33Z Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors Vallance, J. Boyle, Terry Courneya, K. Lynch, B. BACKGROUND: The primary purpose of this study was to determine associations of accelerometer-assessed moderate- to vigorousintensity physical activity (MVPA) and sedentary time with health-related quality of life (HRQoL) and physical function and well-being in colon cancer survivors. METHODS: Colon cancer survivors (N=178) from Alberta, Canada (n=92) and Western Australia (n=86) completed a mailed survey that assessed HRQoL (Functional Assessment of Cancer Therapy-Colorectal), physical function and wellbeing (Trial Outcome Index-Colorectal), and relevant covariates. MVPA and sedentary time were assessed using the Actigraph GT3X1 accelerometer (60-second epochs) via a 7-day monitoring protocol. Average daily MVPA and sedentary time was corrected for wear time and then examined as quartiles. RESULTS: Adjusting for relevant demographic, behavioral, and clinical covariates, a significant difference in HRQoL scores emerged between quartile 1 (Q1) and Q4 (Mdiff=11.5, P=.038). For physical function and wellbeing, a significant difference emerged between Q1 and Q4 (Mdiff=9.1, P=.009). For fatigue, a significant difference emerged between Q1 and Q4 (Mdiff=7.1, P=.05). Significant differences were also observed for between Q1 and Q3 (Mdiff=2.4, P=.041), and Q1 and Q4 (Mdiff=3.5, P=.002) for colorectal cancer-specific symptoms. There were no statistically significant associations of sedentary time with HRQoL, physical function and well-being, fatigue, or colorectal cancer-specific symptoms. CONCLUSIONS: Objectively measured MVPA, but not sedentary time, was associated with better HRQoL, physical function and well-being, and colorectal cancer- specific symptoms in colon cancer survivors. For MVPA, differences met or exceeded contemporary cutpoints for determining clinically important differences. 2014 Journal Article http://hdl.handle.net/20.500.11937/11682 10.1002/cncr.28779 John Wiley & Sons, Inc. unknown |
| spellingShingle | Vallance, J. Boyle, Terry Courneya, K. Lynch, B. Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors |
| title | Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors |
| title_full | Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors |
| title_fullStr | Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors |
| title_full_unstemmed | Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors |
| title_short | Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors |
| title_sort | associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors |
| url | http://hdl.handle.net/20.500.11937/11682 |