Characterisation of Australian Staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system
Serological typing was demonstrated to be more reliable than molecular typing for capsular phenotyping of Australian bovine mastitis-associated Staphylococcus aureus isolates. A relationship between strength of biofilm formation, icaA and icaD genes and extent of mammary tissue damage was apparent....
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| Format: | Thesis |
| Language: | English |
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Curtin University
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/1143 |
| _version_ | 1848743583770738688 |
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| author | Gogoi Tiwari, Jully |
| author_facet | Gogoi Tiwari, Jully |
| author_sort | Gogoi Tiwari, Jully |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Serological typing was demonstrated to be more reliable than molecular typing for capsular phenotyping of Australian bovine mastitis-associated Staphylococcus aureus isolates. A relationship between strength of biofilm formation, icaA and icaD genes and extent of mammary tissue damage was apparent. Distribution of MSCRAMMs and exotoxins, and potential of anti-IL6 and anti IL6-receptor antibodies on mortality of infected mice was determined. Biofilm-embedded S. aureus vaccine offered better protection against mammary tissue damage than the planktonic vaccine. |
| first_indexed | 2025-11-14T05:47:53Z |
| format | Thesis |
| id | curtin-20.500.11937-1143 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:47:53Z |
| publishDate | 2014 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-11432017-02-20T06:39:39Z Characterisation of Australian Staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system Gogoi Tiwari, Jully Serological typing was demonstrated to be more reliable than molecular typing for capsular phenotyping of Australian bovine mastitis-associated Staphylococcus aureus isolates. A relationship between strength of biofilm formation, icaA and icaD genes and extent of mammary tissue damage was apparent. Distribution of MSCRAMMs and exotoxins, and potential of anti-IL6 and anti IL6-receptor antibodies on mortality of infected mice was determined. Biofilm-embedded S. aureus vaccine offered better protection against mammary tissue damage than the planktonic vaccine. 2014 Thesis http://hdl.handle.net/20.500.11937/1143 en Curtin University fulltext |
| spellingShingle | Gogoi Tiwari, Jully Characterisation of Australian Staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system |
| title | Characterisation of Australian Staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system |
| title_full | Characterisation of Australian Staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system |
| title_fullStr | Characterisation of Australian Staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system |
| title_full_unstemmed | Characterisation of Australian Staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system |
| title_short | Characterisation of Australian Staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system |
| title_sort | characterisation of australian staphylococcus aureus isolates of bovine mastitis origin, and development and evaluation of the potential of vaccines for prevention of mastitis using mouse as a model system |
| url | http://hdl.handle.net/20.500.11937/1143 |