Pharmacokinetics and allometric scaling of antimalarial drugs

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Pharmacokinetics and allometric scaling of antimalarial drugs

Allometric scaling was found as a plausible technique for dose determination in children. Permeability and P-glycoprotein efflux transport of antimalarials were determined using in-vitro Caco-2 cells. Mefloquine showed P-glycoprotein inhibition. Amodiaquine, artesunate and artemisone were not P-glyc...

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Bibliographic Details
Main Author:	Senarathna, Senarathna Mudiyanselage Dona Kalyani Ganga
Format:	Thesis
Language:	English
Published:	Curtin University 2015
Online Access:	http://hdl.handle.net/20.500.11937/1139

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