LIM kinase-1 selectively promotes glycoprotein 1b-IX-mediated TXA2 synthesis, platelet activation, and thrombosis

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LIM kinase-1 selectively promotes glycoprotein 1b-IX-mediated TXA2 synthesis, platelet activation, and thrombosis

Current antithrombotic drugs have an adverse effect on bleeding, highlighting the need for new molecular targets for developing antithrombotic drugs that minimally affect hemostasis. Here we show that LIMK1−/− mice have defective arterial thrombosis in vivo but do not differ from wild-type mice with...

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Bibliographic Details
Main Authors:	Estevez, Brian, Stojanovic, Aleksandra, Delaney, M Keegan, O'Brien, Kelly, Berndt, Michael, Ruan, Changgeng, Du, Xaioping
Format:	Journal Article
Published:	American Society of Hematology 2013
Online Access:	http://hdl.handle.net/20.500.11937/11367

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