A molecular tool to assess the pathological relevance of alpha-globin DNA variants

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A molecular tool to assess the pathological relevance of alpha-globin DNA variants

Aim: While the phenotype for heterozygous beta-thalassaemia is straightforward, it is more difficult to confirm a causative relationship for mutations in the alpha-globin genes. The aim of this study was to generate an in vitro system to evaluate the pathological relevance of α-globin mutations. Met...

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Bibliographic Details
Main Authors:	Qadah, T., Finlayson, J., Newbound, C., Pell, N., Jennens, M., Holmes, P., Grey, D., Beilby, J., Ghassemifar, Reza
Format:	Journal Article
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/11254

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