Condom and Oral Contraceptive Use and Risk of Cervical Intraepithelial Neoplasia in Australian Women

Objective: To assess the association between condom use and oral contraceptive consumption and the risk of cervical intraepithelial neoplasia (CIN).Methods: A cross-sectional study was conducted in Perth clinics. A total of 348 women responded to the structured questionnaire. Information sought incl...

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Main Authors: Chih, Hui Jun, Lee, Andy, Colville, Linda, Xu, D., Binns, Colin
Format: Journal Article
Published: Korean Society of Gynecologic Oncology 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/10665
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author Chih, Hui Jun
Lee, Andy
Colville, Linda
Xu, D.
Binns, Colin
author_facet Chih, Hui Jun
Lee, Andy
Colville, Linda
Xu, D.
Binns, Colin
author_sort Chih, Hui Jun
building Curtin Institutional Repository
collection Online Access
description Objective: To assess the association between condom use and oral contraceptive consumption and the risk of cervical intraepithelial neoplasia (CIN).Methods: A cross-sectional study was conducted in Perth clinics. A total of 348 women responded to the structured questionnaire. Information sought included demographic and lifestyle characteristics such as the use of condom for contraception, consumption of oral contraceptive, and duration of oral contraceptive usage. Crude and adjusted odds ratio (OR) and associated 95% confidence interval (CI) were calculated using unconditional logistic regression models and reported as estimates of the relative risk. Results: The prevalence of CIN was found to be 15.8%. The duration of oral contraceptive consumption among women with abnormal Papanicolaou (Pap) smear result indicating CIN was significantly shorter than those without abnormal Pap smear result (mean±SD, 5.6±5.2 years vs. 8.2±7.6 years; p=0.002). Comparing to =3 years usage, prolonged consumption of oral contraceptive for =10 years reduced the risk of CIN (p=0.012). However, use of condom for contraception might not be associated with a reduced risk of CIN after accounting for the effects of confounding factors (adjusted OR, 0.52; 95% CI, 0.05 to 5.11; p=0.577).Conclusion: Use of oral contraceptives, but not condoms, for contraception appeared to be inversely associated with CIN. Prolonged use of oral contraceptive demonstrated its benefits of reducing the risk of CIN.
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spelling curtin-20.500.11937-106652019-05-28T08:30:38Z Condom and Oral Contraceptive Use and Risk of Cervical Intraepithelial Neoplasia in Australian Women Chih, Hui Jun Lee, Andy Colville, Linda Xu, D. Binns, Colin Condom Oral contraceptive Cervical intraepithelial neoplasia Australia Comparative study Objective: To assess the association between condom use and oral contraceptive consumption and the risk of cervical intraepithelial neoplasia (CIN).Methods: A cross-sectional study was conducted in Perth clinics. A total of 348 women responded to the structured questionnaire. Information sought included demographic and lifestyle characteristics such as the use of condom for contraception, consumption of oral contraceptive, and duration of oral contraceptive usage. Crude and adjusted odds ratio (OR) and associated 95% confidence interval (CI) were calculated using unconditional logistic regression models and reported as estimates of the relative risk. Results: The prevalence of CIN was found to be 15.8%. The duration of oral contraceptive consumption among women with abnormal Papanicolaou (Pap) smear result indicating CIN was significantly shorter than those without abnormal Pap smear result (mean±SD, 5.6±5.2 years vs. 8.2±7.6 years; p=0.002). Comparing to =3 years usage, prolonged consumption of oral contraceptive for =10 years reduced the risk of CIN (p=0.012). However, use of condom for contraception might not be associated with a reduced risk of CIN after accounting for the effects of confounding factors (adjusted OR, 0.52; 95% CI, 0.05 to 5.11; p=0.577).Conclusion: Use of oral contraceptives, but not condoms, for contraception appeared to be inversely associated with CIN. Prolonged use of oral contraceptive demonstrated its benefits of reducing the risk of CIN. 2014 Journal Article http://hdl.handle.net/20.500.11937/10665 10.3802/jgo.2014.25.3.183 Korean Society of Gynecologic Oncology fulltext
spellingShingle Condom
Oral contraceptive
Cervical intraepithelial neoplasia
Australia
Comparative study
Chih, Hui Jun
Lee, Andy
Colville, Linda
Xu, D.
Binns, Colin
Condom and Oral Contraceptive Use and Risk of Cervical Intraepithelial Neoplasia in Australian Women
title Condom and Oral Contraceptive Use and Risk of Cervical Intraepithelial Neoplasia in Australian Women
title_full Condom and Oral Contraceptive Use and Risk of Cervical Intraepithelial Neoplasia in Australian Women
title_fullStr Condom and Oral Contraceptive Use and Risk of Cervical Intraepithelial Neoplasia in Australian Women
title_full_unstemmed Condom and Oral Contraceptive Use and Risk of Cervical Intraepithelial Neoplasia in Australian Women
title_short Condom and Oral Contraceptive Use and Risk of Cervical Intraepithelial Neoplasia in Australian Women
title_sort condom and oral contraceptive use and risk of cervical intraepithelial neoplasia in australian women
topic Condom
Oral contraceptive
Cervical intraepithelial neoplasia
Australia
Comparative study
url http://hdl.handle.net/20.500.11937/10665