Molecular and cellular analysis of three novel alpha2-globin gene promoter mutations [HBA2: c.-59C>T], [HBA2: c.-81C>A] and [HBA2: c.-91G>A] reveal varying patterns of transcriptional and translational activities

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Molecular and cellular analysis of three novel alpha2-globin gene promoter mutations [HBA2: c.-59C>T], [HBA2: c.-81C>A] and [HBA2: c.-91G>A] reveal varying patterns of transcriptional and translational activities

While point mutations affecting the promoter region of [beta]-globin gene are widely described, there are no well characterised reports of any point mutations currently found in the promoter of the [alpha]2-globin (HBA2) gene. We present clinical and experimental data for three novel HBA2 gene core...

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Bibliographic Details
Main Authors:	Qadah, T., Finlayson, J., Dennis, M., Ghassemifar, Reza
Format:	Journal Article
Published:	Lippincott Williams & Wilkins, Ltd. 2014
Online Access:	http://hdl.handle.net/20.500.11937/10198

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