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1860799771989508096
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| building |
INTELEK Repository
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| collection |
Online Access
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| collectionurl |
https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072
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| date |
2009-06-24 18:38:01
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| format |
Restricted Document
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| id |
7332
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UniSZA
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| internalnotes |
AHA, American Heart Association. 2000. Heart and stroke guide: Cholesterol statistics 2000. www.americanheart.org. Aqil, F., Ahmad, I. and Mehmood, Z. 2006. Antioxidant and free radical scavenging properties of twelve traditionally used Indian medicinal plants. Turkish Journal of Biology (30): 177 – 183. Anderson, J.W., Jones, A.E. and Riddell-Mason, S. 1994. Ten different dietary fibers have significantly different effects on serum and liver lipids of cholesterol fed rats. Journal of Nutrition 124:78-83. Block, G, Patterson, B. and Subar, A. 1992. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutrition and Cancer 18(1):1-29. Farag, R.S., Badei, A.Z.M.A., Hawed, F.M. and El-Baroty, G.S.A. 1989. Antioxidant activity of some spice essential oils on linoleic acid oxidation in aqueous media. Journal of American Oil Chemists Society (66): 793-799. Huda-Faujan, N., Noriham, A., Norrakiah, A.S. and Babji, A.S. 2009. Antioxidant activity of plants methanolic extracts containing phenolic compounds. African Journal of Biotechnology 8 (3): 484-489. Javanmardi, J., Stusnoff, C., Locke, E. and Vivanco, J.M. 2003. Antioxidant activity and total phenolic content of Iranian Ocimum accessions. Food Chemistry (83): 547-550. Koshy, A.S., Anila, L. and Vijayalakshmi, N. R. 2001. Flavonoids from garcinia cambogia lower lipid levels in hypercholesterolemic rats. Journal of Food Chemistry 72: 289-294. Kikuzaki, H. and Nakatani, N. 1993. Antioxidants effect of water extract of Aegle marmelos fruits in streptozotocin diabetic rats. Journal of Ethnopharmacology (87): 207-2010. Lorgeril, M., Renaud, S., Mamelle, N., Salen, P., Martin, J.l., Monjoud, I., Guidollel, J., Toubul, P. and Delaye, J. 1994. Mediterranean alpha-linolic acid-rich diet in secondary prevention of coronary heart disease. Lancet 343: 1454-1459. Lees, A.M., Mok, H.Y., Lees, R.S., et al. 1993. Effect on blood lipids of very high intakes of fiber in diet low in saturated fat and cholesterol. New England Journal of Medicine 329:21- 26. Lee, V. T. 2002. Current status of the Vietnamase rural economy and measures for its vitalation and improving farmer’s income. 9th JIRCAS International Symposium 2002- ‘Value-Addition to Agriculture Products’. 42-48. Maznah, I., Elizabeth, M., Azlina, M.D., Asmah, R. and Asmah, Y. 2000. Chemical composition and antioxidant activity of Strobilanthes crispus leaf extract. Journal of Nutrition and Biochemistry (11): 536-542. Mohd Adzim Khalili, R., Norhayati, A.H., Rokiah, M.Y., Asmah, R., Mohd Nasir, M.T. and Siti Muskinah, M. 2006. Proximate composition and selected mineral determination in organically grown red pitaya (Hylocereus sp.). Journal of Tropical Agriculture and Food Science 34 (2): 269-276. Ottolenghi, H. 1959. Interaction of ascorbic acid and mitochondria lipids. Archives of Biochemistry and Biophysics (79): 355-357. Raveh, E., Nerd, A. and Mizrahi, Y. 1998. Responses of two hemi epiphytic fruit crop cacti to different degrees of shde. Scientia Horticulturea 73: 151-164. Stintzing, F.C., Scheiber, A. and Carle, R. 2002. Betacyanin in fruits from red-purple pitaya (Hylocereus polyhizus) (Weber) Brintton and Rose. Food Chemistry 77:101-106. Steinmetz, K. A. and Potter, J.D. 1991. Vegetables, fruit and cancer. I. Epidemiology. Cancer Causes Control 2(5):325-57. Partiff, V.J., Rubba, P., Bolton, C., Marrota, G., Hartog, M. and Mancini, M. 1994. A comparison of antioxidant status and free radical peroxidation of plasma lipoproteins in healthy young persons from Naples and Bristol. Uer. Heart Journal 15: 871-876. Velioglu, Y.S., Mazza, G., Gao, L. and Oomah, B.D. 1998. Antioxidant activity and total phenolics in selected fruits, vegetables and grain products. Journal of Agricultural and Food Chemistry (46):4113-4117. Wybraniec, S., Platzner, I., Geresh, S., Gottlieb, H.E., Haimberg, M., Mogilnitzki, M., et al. 2001. Betacyanin from vine cactus Hylocereus polyrhizus. Phytochemistry 58:1209-1212. Zulet, M. A., Barber, A., Garcin, H., Higueret, P. and Martinez, J. A. 1999. Alterations in carbohydrate and lipid metabolism induced by a diet rich in coconut oil and cholesterol in a rats model. Journal of American College of Nutrition 18: 36–42.
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2744-01-FH02-FPBSM-14-00407.pdf
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| person |
John
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| recordtype |
oai_dc
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| resourceurl |
https://intelek.unisza.edu.my/intelek/pages/view.php?ref=7332
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| spelling |
7332 https://intelek.unisza.edu.my/intelek/pages/view.php?ref=7332 https://intelek.unisza.edu.my/intelek/pages/search.php?search=!collection407072 Restricted Document Article Journal application/pdf 10 1.6 Adobe Acrobat Pro DC 20 Paper Capture Plug-in John 2009-06-24 18:38:01 2744-01-FH02-FPBSM-14-00407.pdf UniSZA Private Access Hypocholesterolemic effect of red pitaya (Hylocereus sp.) on hypercholesterolemia induced rats International Food Research Journal This study was carried out to evaluate the total phenolic content and anti-oxidant activity of methanolic extract of red pitaya, and hypocholesterolemic effect of red pitaya (Hylocereus sp.) on lipid profiles status on hypercholesterolemia induced rats. From the analysis, total phenolic content in red pitaya is 46.06 ± 1.77 mg GAE/100 g fresh weight and antioxidant activity is 76.10% using FTC method. TBA analysis also showed red pitaya extract had high antioxidant effect (72.90%). An in-vivo study also showed red pitaya has hypocholesterolemic effect on induced hypercholesterolemia rats. After 11 weeks of study, total blood cholesterol significant decrease (p<0.05) in the groups supplement with red pitaya. The total cholesterol (TC) level for group PF1 were reduced from 3.356 mmol/L to 1.707 mmol/L (49.14%), group PF2 reduced from 3.435 mmol/L to 1.487 mmol/L (56.72%) and group PF3 reduced from 3.448 mmol/L to 1.412 mmol/L (59.06%) as compare to baseline respectively. The mean total cholesterol level in both negative (N – 5.12%) and positive controls (group HC – 13.79%) were not significantly different (p<0.05). The mean triglycerides (TG) level for all groups had shown a reduction (p<0.05) with value of 23.87% (group N), 22.674% (group HC), 42.81% (group PF1), 52.82% (group PF2) and 59.52% (group PF3) as compare to baseline levels. The mean HDL level increased by about 2.12% (group N), 19.31% (group PF1), 21.93% (group PF2) and much higher increase in group PF3 (34.42%). The mean LDL decreased by about 39.06% (PF3), 15.10% (PF2), 1.50% (PF1) and 4.33% (group N). The positive control has showed significantly increase with the mean value for 25.68%. In conclusion, all groups that received red pitaya supplementation has high antioxidant properties and showed a good results in managing of lipid profile. It was suggested that the consumption of red pitaya demonstrated the potential to reduce dyslipidemia and play a role in the prevention of cardiovascular disease. 431-440 AHA, American Heart Association. 2000. Heart and stroke guide: Cholesterol statistics 2000. www.americanheart.org. Aqil, F., Ahmad, I. and Mehmood, Z. 2006. Antioxidant and free radical scavenging properties of twelve traditionally used Indian medicinal plants. Turkish Journal of Biology (30): 177 – 183. Anderson, J.W., Jones, A.E. and Riddell-Mason, S. 1994. Ten different dietary fibers have significantly different effects on serum and liver lipids of cholesterol fed rats. Journal of Nutrition 124:78-83. Block, G, Patterson, B. and Subar, A. 1992. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutrition and Cancer 18(1):1-29. Farag, R.S., Badei, A.Z.M.A., Hawed, F.M. and El-Baroty, G.S.A. 1989. Antioxidant activity of some spice essential oils on linoleic acid oxidation in aqueous media. Journal of American Oil Chemists Society (66): 793-799. Huda-Faujan, N., Noriham, A., Norrakiah, A.S. and Babji, A.S. 2009. Antioxidant activity of plants methanolic extracts containing phenolic compounds. African Journal of Biotechnology 8 (3): 484-489. Javanmardi, J., Stusnoff, C., Locke, E. and Vivanco, J.M. 2003. Antioxidant activity and total phenolic content of Iranian Ocimum accessions. Food Chemistry (83): 547-550. Koshy, A.S., Anila, L. and Vijayalakshmi, N. R. 2001. Flavonoids from garcinia cambogia lower lipid levels in hypercholesterolemic rats. Journal of Food Chemistry 72: 289-294. Kikuzaki, H. and Nakatani, N. 1993. Antioxidants effect of water extract of Aegle marmelos fruits in streptozotocin diabetic rats. Journal of Ethnopharmacology (87): 207-2010. Lorgeril, M., Renaud, S., Mamelle, N., Salen, P., Martin, J.l., Monjoud, I., Guidollel, J., Toubul, P. and Delaye, J. 1994. Mediterranean alpha-linolic acid-rich diet in secondary prevention of coronary heart disease. Lancet 343: 1454-1459. Lees, A.M., Mok, H.Y., Lees, R.S., et al. 1993. Effect on blood lipids of very high intakes of fiber in diet low in saturated fat and cholesterol. New England Journal of Medicine 329:21- 26. Lee, V. T. 2002. Current status of the Vietnamase rural economy and measures for its vitalation and improving farmer’s income. 9th JIRCAS International Symposium 2002- ‘Value-Addition to Agriculture Products’. 42-48. Maznah, I., Elizabeth, M., Azlina, M.D., Asmah, R. and Asmah, Y. 2000. Chemical composition and antioxidant activity of Strobilanthes crispus leaf extract. Journal of Nutrition and Biochemistry (11): 536-542. Mohd Adzim Khalili, R., Norhayati, A.H., Rokiah, M.Y., Asmah, R., Mohd Nasir, M.T. and Siti Muskinah, M. 2006. Proximate composition and selected mineral determination in organically grown red pitaya (Hylocereus sp.). Journal of Tropical Agriculture and Food Science 34 (2): 269-276. Ottolenghi, H. 1959. Interaction of ascorbic acid and mitochondria lipids. Archives of Biochemistry and Biophysics (79): 355-357. Raveh, E., Nerd, A. and Mizrahi, Y. 1998. Responses of two hemi epiphytic fruit crop cacti to different degrees of shde. Scientia Horticulturea 73: 151-164. Stintzing, F.C., Scheiber, A. and Carle, R. 2002. Betacyanin in fruits from red-purple pitaya (Hylocereus polyhizus) (Weber) Brintton and Rose. Food Chemistry 77:101-106. Steinmetz, K. A. and Potter, J.D. 1991. Vegetables, fruit and cancer. I. Epidemiology. Cancer Causes Control 2(5):325-57. Partiff, V.J., Rubba, P., Bolton, C., Marrota, G., Hartog, M. and Mancini, M. 1994. A comparison of antioxidant status and free radical peroxidation of plasma lipoproteins in healthy young persons from Naples and Bristol. Uer. Heart Journal 15: 871-876. Velioglu, Y.S., Mazza, G., Gao, L. and Oomah, B.D. 1998. Antioxidant activity and total phenolics in selected fruits, vegetables and grain products. Journal of Agricultural and Food Chemistry (46):4113-4117. Wybraniec, S., Platzner, I., Geresh, S., Gottlieb, H.E., Haimberg, M., Mogilnitzki, M., et al. 2001. Betacyanin from vine cactus Hylocereus polyrhizus. Phytochemistry 58:1209-1212. Zulet, M. A., Barber, A., Garcin, H., Higueret, P. and Martinez, J. A. 1999. Alterations in carbohydrate and lipid metabolism induced by a diet rich in coconut oil and cholesterol in a rats model. Journal of American College of Nutrition 18: 36–42.
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| spellingShingle |
Hypocholesterolemic effect of red pitaya (Hylocereus sp.) on hypercholesterolemia induced rats
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| summary |
This study was carried out to evaluate the total phenolic content and anti-oxidant activity of methanolic extract of red pitaya, and hypocholesterolemic effect of red pitaya (Hylocereus sp.) on lipid profiles status on hypercholesterolemia induced rats. From the analysis, total phenolic content in red pitaya is 46.06 ± 1.77 mg GAE/100 g fresh weight and antioxidant activity is 76.10% using FTC method. TBA analysis also showed red pitaya extract had high antioxidant effect (72.90%). An in-vivo study also showed red pitaya has hypocholesterolemic effect on induced hypercholesterolemia rats. After 11 weeks of study, total blood cholesterol significant decrease (p<0.05) in the groups supplement with red pitaya. The total cholesterol (TC) level for group PF1 were reduced from 3.356 mmol/L to 1.707 mmol/L (49.14%), group PF2 reduced from 3.435 mmol/L to 1.487 mmol/L (56.72%) and group PF3 reduced from 3.448 mmol/L to 1.412 mmol/L (59.06%) as compare to baseline respectively. The mean total cholesterol level in both negative (N – 5.12%) and positive controls (group HC – 13.79%) were not significantly different (p<0.05). The mean triglycerides (TG) level for all groups had shown a reduction (p<0.05) with value of 23.87% (group N), 22.674% (group HC), 42.81% (group PF1), 52.82% (group PF2) and 59.52% (group PF3) as compare to baseline levels. The mean HDL level increased by about 2.12% (group N), 19.31% (group PF1), 21.93% (group PF2) and much higher increase in group PF3 (34.42%). The mean LDL decreased by about 39.06% (PF3), 15.10% (PF2), 1.50% (PF1) and 4.33% (group N). The positive control has showed significantly increase with the mean value for 25.68%. In conclusion, all groups that received red pitaya supplementation has high antioxidant properties and showed a good results in managing of lipid profile. It was suggested that the consumption of red pitaya demonstrated the potential to reduce dyslipidemia and play a role in the prevention of cardiovascular disease.
|
| title |
Hypocholesterolemic effect of red pitaya (Hylocereus sp.) on hypercholesterolemia induced rats
|
| title_full |
Hypocholesterolemic effect of red pitaya (Hylocereus sp.) on hypercholesterolemia induced rats
|
| title_fullStr |
Hypocholesterolemic effect of red pitaya (Hylocereus sp.) on hypercholesterolemia induced rats
|
| title_full_unstemmed |
Hypocholesterolemic effect of red pitaya (Hylocereus sp.) on hypercholesterolemia induced rats
|
| title_short |
Hypocholesterolemic effect of red pitaya (Hylocereus sp.) on hypercholesterolemia induced rats
|
| title_sort |
hypocholesterolemic effect of red pitaya (hylocereus sp.) on hypercholesterolemia induced rats
|